G
George L. Mutter
Researcher at Brigham and Women's Hospital
Publications - 147
Citations - 11589
George L. Mutter is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Endometrial intraepithelial neoplasia & Endometrial cancer. The author has an hindex of 55, co-authored 145 publications receiving 10954 citations. Previous affiliations of George L. Mutter include NewYork–Presbyterian Hospital & Case Western Reserve University.
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Journal ArticleDOI
Benign endometrial hyperplasia sequence and endometrial intraepithelial neoplasia.
TL;DR: The use of an internal standard for cytology assessment, combined with the distinctive topography of a clonal process, enables the diagnosis of EIN lesions with a long-term cancer risk 45-fold greater than that of their benign endometrial hyperplasia counterparts.
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Distinct developmental patterns of c-mos protooncogene expression in female and male mouse germ cells.
TL;DR: In situ hybridization analysis of c-mos expression in histological sections of mouse ovaries revealed that oocytes are the predominant if not exclusive source of c.mos transcripts, suggesting that the c-Mos gene product may have a function in normal germ-cell differentiation or early embryogenesis.
Journal ArticleDOI
Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis
Jonathan L. Hecht,Tan A. Ince,Jan P. A. Baak,Heather E Baker,Maryann W Ogden,George L. Mutter +5 more
TL;DR: Subjective application of criteria for diagnosis of EIN correlates well with objective morphometry and successfully segregates patients into high and low cancer risk subgroups with better reproducibility than atypical hyperplasia diagnosis.
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High-grade fimbrial-ovarian carcinomas are unified by altered p53, PTEN and PAX2 expression
Michael H. Roh,Yosuf Yassin,Alexander Miron,Karishma K. Mehra,Mitra Mehrad,Nicolas M. Monte,George L. Mutter,Marisa R. Nucci,Geng Ning,Frank McKeon,Michelle S. Hirsch,Xian Wa,Xian Wa,Christopher P. Crum +13 more
TL;DR: High-grade müllerian carcinomas share identical frequencies of altered or reduced expression of p53, PTEN and PAX2, all of which can be appreciated in tubal intraepithelial carcinomas.