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George W. Nelson

Researcher at Leidos

Publications -  84
Citations -  14306

George W. Nelson is an academic researcher from Leidos. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 44, co-authored 82 publications receiving 13204 citations. Previous affiliations of George W. Nelson include Science Applications International Corporation & National Institutes of Health.

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Causal and Putative Pathogenic Mutations Identified in 38.6% of Children with Primary SRNS in South Africa

TL;DR: Screening all Black African children presenting with NS for NPHS2 p.V260E will provide a precision diagnosis of SR-FSGS and inform clinical management, and report four novel variants in INF2, PLCE1, ACTN4 and TRPC6.
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A mouse recapitulating APOL1-associated kidney disease

TL;DR: A mouse model expressing variant APOL1 that recapitulates human kidney disease and leads to caspase-1-dependent pyroptosis is generated, which opens the door for the development of new druggable targets to treat AP OL1-mediated kidney disease.
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Contents Vol. 29, 2009

Tejas V. Patel, +114 more