G
George W. Nelson
Researcher at Leidos
Publications - 84
Citations - 14306
George W. Nelson is an academic researcher from Leidos. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 44, co-authored 82 publications receiving 13204 citations. Previous affiliations of George W. Nelson include Science Applications International Corporation & National Institutes of Health.
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Journal ArticleDOI
Haemophilia Inhibitor Genetics Study - evaluation of a model for studies of complex diseases using linkage and association methods.
Erik Berntorp,Jan Astermark,Sharyne Donfield,George W. Nelson,Johannes Oldenburg,Amy D. Shapiro,Donna DiMichele,Bruce M. Ewenstein,Edward D. Gomperts,Cheryl A. Winkler +9 more
TL;DR: This work aims to demonstrate the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.
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NPHS2 V260E Is a Frequent Cause of Steroid-Resistant Nephrotic Syndrome in Black South African Children
Kareshma Asharam,Rajendra Bhimma,Victor A. David,Hoosen Coovadia,Hoosen Coovadia,Wenkosi P. Qulu,Thajasvarie Naicker,Christopher E. Gillies,Virginia Vega-Warner,Randall C. Johnson,Sophie Limou,Jeffrey B. Kopp,Mathew Sampson,George W. Nelson,Cheryl A. Winkler +14 more
TL;DR: NPHS2 260E/E was present in one-third of black FSGS patients, was absent in black controls and Indian patients, and affected patients were unresponsive to therapy.
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ISHAPE: new rapid and accurate software for haplotyping
Olivier Delaneau,Olivier Delaneau,Cédric Coulonges,Cédric Coulonges,Pierre-Yves Boëlle,George W. Nelson,Jean-Louis Spadoni,Jean-François Zagury,Jean-François Zagury +8 more
TL;DR: The results show that the Ishape heuristic approach for haplotyping is very competitive in terms of accuracy and speed and deserves to be evaluated extensively for possible future widespread use.
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Relationship between human leukocyte antigen alleles and risk of Kaposi’s sarcoma in Cameroon
Elena M. Cornejo Castro,Brian J. Morrison,Vickie Marshall,Nazzarena Labo,Wendell Miley,Nathan Clements,George W. Nelson,Paul Ndom,Kristen Stolka,Jennifer Hemingway-Foday,Mahamat Abassora,Xiaojiang Gao,Jennifer S. Smith,Mary Carrington,Denise Whitby +14 more
TL;DR: This study provides additional understanding of genetic determinants of KS and their implications in disease pathogenesis and identifies the HLA-B and -DQA1 loci as possible risk factors for endemic KS.
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Association of Inhibitory Killer Cell Immunoglobulin-like Receptor Ligands With Higher Plasmodium falciparum Parasite Prevalence.
Jean C. Digitale,Perri C. Callaway,Perri C. Callaway,Maureen Martin,George W. Nelson,Mathias Viard,John Rek,Emmanuel Arinaitwe,Grant Dorsey,Moses R. Kamya,Mary Carrington,Isabel Rodriguez-Barraquer,Margaret E. Feeney +12 more
TL;DR: Data indicate that stronger KIR-mediated inhibition confers a higher risk of P. falciparum parasitemia and suggest that Kir-expressing effector cells play a role in mediating anti-parasite immunity.