G
Giammarco Fava
Researcher at Marche Polytechnic University
Publications - 43
Citations - 1950
Giammarco Fava is an academic researcher from Marche Polytechnic University. The author has contributed to research in topics: Cholangiocyte & Cholangiocyte proliferation. The author has an hindex of 24, co-authored 43 publications receiving 1798 citations. Previous affiliations of Giammarco Fava include Scott & White Hospital & Texas A&M University.
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Journal ArticleDOI
Vascular Endothelial Growth Factor Stimulates Rat Cholangiocyte Proliferation Via an Autocrine Mechanism
Eugenio Gaudio,Barbara Barbaro,Barbara Barbaro,Domenico Alvaro,Shannon Glaser,Heather Francis,Yoshiyuki Ueno,Cynthia J. Meininger,Antonio Franchitto,Paolo Onori,Marco Marzioni,Silvia Taffetani,Giammarco Fava,George Stoica,Julie Venter,Ramona Reichenbach,Sharon De Morrow,Ryun Summers,Gianfranco Alpini +18 more
TL;DR: VEGF mediates the adaptive proliferative response of cholangiocytes to cholestasis and is found to be amplified in BDL cholangsiocytes.
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Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin
Marco Marzioni,Shannon Glaser,Heather Francis,Luca Marucci,Antonio Benedetti,Domenico Alvaro,Silvia Taffetani,Yoshiyuki Ueno,Tania Roskams,Jo Lynne Phinizy,J Venter,Giammarco Fava,Gene LeSage,Gianfranco Alpini,Gianfranco Alpini +14 more
TL;DR: The existence of an autocrine loop based on serotonin that limits the growth of the biliary tree in the course of chronic cholestasis is observed and might open new approaches for the management of cholangiopathies.
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cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway.
Heather Francis,Shannon Glaser,Yoshiyuki Ueno,Gene LeSage,Luca Marucci,Antonio Benedetti,Silvia Taffetani,Marco Marzioni,Domenico Alvaro,Julie Venter,Ramona Reichenbach,Giammarco Fava,Jo Lynne Phinizy,Gianfranco Alpini,Gianfranco Alpini +14 more
TL;DR: Modulation of the PKA/Src/MEK/ERK1/2 pathway may be important in the regulation of cholangiocyte growth and secretion observed in cholestatic liver diseases.
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VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: The ALICE-1 study
Mario Scartozzi,Luca Faloppi,Gianluca Svegliati Baroni,Cristian Loretelli,Fabio Piscaglia,Massimo Iavarone,Pierluigi Toniutto,Giammarco Fava,Samuele De Minicis,Alessandra Mandolesi,Maristella Bianconi,Riccardo Giampieri,Alessandro Granito,Floriana Facchetti,Davide Bitetto,Sara Marinelli,L. Venerandi,Sara Vavassori,S. Gemini,Antonietta D'Errico,Massimo Colombo,Luigi Bolondi,Italo Bearzi,Antonio Benedetti,Stefano Cascinu +24 more
TL;DR: Once prospectively validated, the analysis of VEGF and VEGFR SNPs may represent a clinical tool to better identify HCC patients more likely to benefit from sorafenib.
Journal ArticleDOI
Heterogeneity of the intrahepatic biliary epithelium
Shannon Glaser,Heather Francis,Sharon DeMorrow,Gene LeSage,Giammarco Fava,Marco Marzioni,Julie Venter,Gianfranco Alpini +7 more
TL;DR: The objectives of this review are to outline the recent findings related to the morphological heterogeneity of the biliary epithelium and the heterogeneous pathophysiological responses of different sized bile ducts to liver gastrointestinal hormones and peptides and liver injury/toxins with changes in apoptotic, proliferative and secretory activities.