G
Giovanni Ristori
Researcher at Sapienza University of Rome
Publications - 146
Citations - 4017
Giovanni Ristori is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Multiple sclerosis & T cell. The author has an hindex of 30, co-authored 131 publications receiving 3489 citations.
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Journal ArticleDOI
A “candidate-interactome” aggregate analysis of genome-wide association data in multiple sclerosis
Rosella Mechelli,Renato Umeton,Claudia Policano,Viviana Annibali,Giulia Coarelli,Vito A. G. Ricigliano,Danila Vittori,Arianna Fornasiero,Maria Chiara Buscarinu,Silvia Romano,Marco Salvetti,Giovanni Ristori +11 more
TL;DR: The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology, and also other viruses have a similar potential, though probably less relevant in epidemiological terms.
Journal ArticleDOI
CD161highCD8+T cells bear pathogenetic potential in multiple sclerosis
Viviana Annibali,Giovanni Ristori,Daniela F. Angelini,Barbara Serafini,Rosella Mechelli,Stefania Cannoni,Silvia Romano,Andrea Paolillo,Hadi Abderrahim,Adamo Diamantini,Giovanna Borsellino,Francesca Aloisi,Luca Battistini,Marco Salvetti +13 more
TL;DR: Variations of CD161 expression on CD8(+) T cells identify a subset of lymphocytes with proinflammatory characteristics that have not been previously reported in multiple sclerosis and are likely to contribute to disease immunopathology.
Journal Article
Phenotypic and cytokine analysis of human peripheral blood gamma delta T cells expressing NK cell receptors.
Luca Battistini,Giovanna Borsellino,Gregory S. Sawicki,Fabrizio Poccia,Marco Salvetti,Giovanni Ristori,Celia F. Brosnan +6 more
TL;DR: The results suggest that activation of most gamma delta T cells is regulated by signaling events occurring via both the TCR and the NKR, and show that peripheral blood gammaDelta T cells may function as a source of the proinflammatory cytokines IFN-gamma and TNF-alpha.
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Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial
Silvia Romano,Giulia Coarelli,Christian Marcotulli,Luca Leonardi,Francesca Piccolo,Maria Spadaro,Marina Frontali,Michela Ferraldeschi,Maria Chiara Vulpiani,Federica Ponzelli,Marco Salvetti,Francesco Orzi,Antonio Petrucci,Nicola Vanacore,Carlo Casali,Giovanni Ristori +15 more
TL;DR: The findings lend support to the idea that riluzole could be a treatment for cerebellar ataxia, and longer studies and disease-specific trials are needed to confirm whether these findings can be applied in clinical practice.
Journal ArticleDOI
Use of Bacille Calmette-Guèrin (BCG) in multiple sclerosis.
Giovanni Ristori,Maria Gabriella Buzzi,Umberto Sabatini,Elisabetta Giugni,Stefano Bastianello,F. Viselli,Carla Buttinelli,Serena Ruggieri,Claudio Colonnese,C. Pozzilli,Marco Salvetti +10 more
TL;DR: Adjuvant therapy with BCG vaccine was safe and merits study in MS and MRI activity was significantly reduced.