Viviana Annibali

TL;DR: The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology, and also other viruses have a similar potential, though probably less relevant in epidemiological terms.

TL;DR: MRI lesion load, OCB and age at CIS are validated as the strongest independent predictors of conversion to CDMS in this multicentre setting.

TL;DR: Variations of CD161 expression on CD8(+) T cells identify a subset of lymphocytes with proinflammatory characteristics that have not been previously reported in multiple sclerosis and are likely to contribute to disease immunopathology.

TL;DR: The FDA yielded three significant discriminant functions based on age, SOS, Ca, Fe, Si, Sn, V, Zn and Zr, and identified disease-specific profiles of element imbalances, thus showing the appropriateness of the "omics" approach.

TL;DR: The relatively high proportion of IP changes in RR-MS patients seems to confirmed the work hypothesis and warrants more work to confirm the result on a larger sample, and to understand the implications for related immunological disturbances and intestinal microbiota alterations.