G
Guillaume Butler-Laporte
Researcher at McGill University
Publications - 72
Citations - 1522
Guillaume Butler-Laporte is an academic researcher from McGill University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 10, co-authored 44 publications receiving 408 citations. Previous affiliations of Guillaume Butler-Laporte include Jewish General Hospital & McGill University Health Centre.
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Journal ArticleDOI
Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis.
Guillaume Butler-Laporte,Alexander Lawandi,Ian Schiller,Mandy Yao,Nandini Dendukuri,Emily G. McDonald,Emily G. McDonald,Todd C. Lee,Todd C. Lee +8 more
TL;DR: In this article, the authors conducted a systematic review to assess the diagnostic accuracy of saliva nucleic acid amplification testing (NAAT) for coronavirus disease 2019 (COVID-19) and concluded that salivary NAAT diagnostic accuracy is similar to that of nasopharyngeal swab NAAT, especially in the ambulatory setting.
Journal ArticleDOI
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity.
Sirui Zhou,Guillaume Butler-Laporte,Tomoko Nakanishi,David R. Morrison,Jonathan Afilalo,Marc Afilalo,Laetitia Laurent,Maik Pietzner,Nicola D. Kerrison,Kaiqiong Zhao,Elsa Brunet-Ratnasingham,Danielle Henry,Nofar Kimchi,Zaman Afrasiabi,Nardin Rezk,Meriem Bouab,Louis Petitjean,Charlotte Guzman,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yiheng Chen,Michaël Chassé,Madeleine Durand,Clare Paterson,Johan Normark,Robert Frithiof,Miklos Lipcsey,Michael Hultström,Celia M. T. Greenwood,Hugo Zeberg,Claudia Langenberg,Claudia Langenberg,Elin Thysell,Michael Pollak,Vincent Mooser,Vincenzo Forgetta,Daniel Kaufmann,J. Brent Richards +41 more
TL;DR: In this article, a two-sample Mendelian randomization (MR) study was conducted to identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility and severity, rapidly scanning hundreds of circulating proteins while reducing bias due to reverse causation and confounding.
Journal Article
Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis (Jan, 10.1001/jamainternmed.2020.8876, 2021)
TL;DR: The results suggest that saliva NAAT diagnostic accuracy is similar to that of nasopharyngeal swab NAAT, especially in the ambulatory setting, and support larger-scale research on the use of salivaNAAT as an alternative to nasoph throat swabs.
Journal ArticleDOI
Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study
Guillaume Butler-Laporte,Tomoko Nakanishi,Vincent Mooser,David R. Morrison,Tala Abdullah,Olumide Adeleye,Noor Mamlouk,Nofar Kimchi,Nofar Kimchi,Zaman Afrasiabi,Nardin Rezk,Annarita Giliberti,Alessandra Renieri,Yiheng Chen,Sirui Zhou,Vincenzo Forgetta,J. Brent Richards +16 more
TL;DR: In this paper, a 2-sample Mendelian randomization (MR) was used to assess evidence supporting a causal effect of circulating 25-hydroxy vitamin D (25OHD) levels on COVID-19 susceptibility and severity.
Journal ArticleDOI
Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19
Jennifer E. Huffman,Guillaume Butler-Laporte,Atlas Khan,Erola Pairo-Castineira,Theodore G. Drivas,Gina M. Peloso,Tomoko Nakanishi,Andrea Ganna,Anurag Verma,J Kenneth Baillie,Krzysztof Kiryluk,J. Brent Richards,Hugo Zeberg +12 more
TL;DR: In this paper , the OAS1/2/3 cluster was identified as a risk locus for severe COVID-19 among individuals of European ancestry, with a protective haplotype of approximately 75 kilobases (kb) derived from Neanderthals in the chromosomal region 12q24.13.