N
Noor Almamlouk
Researcher at McGill University
Publications - 5
Citations - 180
Noor Almamlouk is an academic researcher from McGill University. The author has contributed to research in topics: Gene & Internal medicine. The author has an hindex of 2, co-authored 3 publications receiving 53 citations. Previous affiliations of Noor Almamlouk include Jewish General Hospital.
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Journal ArticleDOI
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity.
Sirui Zhou,Guillaume Butler-Laporte,Tomoko Nakanishi,David R. Morrison,Jonathan Afilalo,Marc Afilalo,Laetitia Laurent,Maik Pietzner,Nicola D. Kerrison,Kaiqiong Zhao,Elsa Brunet-Ratnasingham,Danielle Henry,Nofar Kimchi,Zaman Afrasiabi,Nardin Rezk,Meriem Bouab,Louis Petitjean,Charlotte Guzman,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yiheng Chen,Michaël Chassé,Madeleine Durand,Clare Paterson,Johan Normark,Robert Frithiof,Miklos Lipcsey,Michael Hultström,Celia M. T. Greenwood,Hugo Zeberg,Claudia Langenberg,Claudia Langenberg,Elin Thysell,Michael Pollak,Vincent Mooser,Vincenzo Forgetta,Daniel Kaufmann,J. Brent Richards +41 more
TL;DR: In this article, a two-sample Mendelian randomization (MR) study was conducted to identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility and severity, rapidly scanning hundreds of circulating proteins while reducing bias due to reverse causation and confounding.
Posted ContentDOI
Circulating Proteins Influencing COVID-19 Susceptibility and Severity: a Mendelian Randomization Study
Sirui Zhou,Sirui Zhou,Guillaume Butler-Laporte,Guillaume Butler-Laporte,Tomoko Nakanishi,David R. Morrison,Jonathan Afilalo,Marc Afilalo,Laetitia Laurent,Maik Pietzner,Nicola D. Kerrison,Kaiqiong Zhao,Kaiqiong Zhao,Elsa Brunet-Ratnasingham,Danielle Henry,Nofar Kimchi,Zaman Afrasiabi,Nardin Rezk,Meriem Bouab,Charlotte Guzman,Louis Petitjean,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yiheng Chen,Madeleine Durand,Michaël Chassé,Johan Normark,Elin Thysell,Robert Frithiof,Miklos Lipcsey,Michael Hultström,Clare Paterson,Michael Pollak,Hugo Zeberg,Celia M. T. Greenwood,Celia M. T. Greenwood,Claudia Langenberg,Claudia Langenberg,Vincent Mooser,Vincenzo Forgetta,Daniel Kaufmann,Brent Richards +45 more
TL;DR: It was found that a standard deviation increase in OAS1 levels was associated with reduced COVID-19 death or ventilation, and available medicines, such as interferon-beta-1b, increase Oas1 and could be explored for their effect on CO VID-19 susceptibility and severity.
Posted ContentDOI
Circulating proteins to predict adverse COVID-19 outcomes
Chen-Yang Su Mr.,Chen-Yang Su Mr.,Sirui Zhou,Sirui Zhou,Edgar Gonzalez-Kozlova,Guillaume Butler-Laporte,Guillaume Butler-Laporte,Elsa Brunet-Ratnasingham,Tomoko Nakanishi,Wonseok Jeon,David R. Morrison,Laetitia Laurent,Joanthan Afilalo,Joanthan Afilalo,Marc Afilalo,Danielle Henry,Yiheng Chen,Yiheng Chen,Julia Carrasco-Zanini,Yossi Farjoun,Maik Pietzner,Maik Pietzner,Nofar Kimchi,Zaman Afrasiabi,Nardin Rezk,Meriem Bouab,Louis Petitjean,Charlotte Guzman,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yara Moussa,Chantal DeLuca,Naomi Duggan,Erwin Schurr,Nathalie Brassard,Madeleine Durand,Diane Marie Del Valle,Ryan Thompson,Mario A. Cedillo,Eric E. Schadt,Kai Nie,Nicole W. Simons,Konstantinos Mouskas,Nicolas Zaki,Manishkumar Patel,Hui Xie,Jocelyn Harris,Robert Marvin,Esther Cheng,Kevin Tuballes,Kimberly Argueta,Ieisha Scott,Celia M. T. Greenwood,Celia M. T. Greenwood,Clare Paterson,Michael A Hinterberg,Claudia Langenberg,Claudia Langenberg,Vincenzo Forgetta,Joelle Pineau,Vincent Mooser,Thomas U. Marron,Noam D. Beckmann,Ephraim Kenigsberg,Seunghee Kim-Schulze,Alexander W. Charney,Sacha Gnjatic,Daniel Kaufmann,Miriam Merad,J. Brent Richards +73 more
TL;DR: In this article, the authors measured 4,701 circulating human protein abundances in two independent cohorts totaling 986 individuals and trained prediction models including protein abundance and clinical risk factors to predict adverse COVID-19 outcomes.
Journal ArticleDOI
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals
Guillaume Butler-Laporte,Edgar Gonzalez-Kozlova,Chen-Yang Su,Sirui Zhou,Tomoko Nakanishi,Elsa Brunet-Ratnasingham,David R. Morrison,Lætitia Laurent,Jonathan Afilalo,Marc Afilalo,D. Henry,Yiheng Chen,Julia Carrasco-Zanini,Yossi Farjoun,Maik Pietzner,N. A. Kimchi,Zaman Afrasiabi,Nardin Rezk,M. Bouab,Louis Petitjean,Charlotte Guzman,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yara Moussa,Chantal DeLuca,N Duggan,Erwin Schurr,Nathalie Brassard,Madeleine Durand,Diane Marie Del Valle,Ryan F. Thompson,Mario A. Cedillo,Eric E. Schadt,Kai Nie,Nicole W. Simons,Konstantinos Mouskas,Nicolas Zaki,Hui Xie,Kimberly Argueta,Ieisha Scott,Charuta Agashe,Priyal Agrawal,Alara Akyatan,Kasey Alesso-Carra,Eziwoma Alibo,Kelvin Alvarez,Angelo Amabile,Carmen Argmann,S. Ascolillo,Rasheed A. Bailey,Craig Batchelor,Aviva G. Beckmann,Priya Begani,Jessica Le Berichel,Dusan Bogunovic,Swaroop Bose,Cansu Cimen Bozkus,Paloma Bravo,Mark Buckup,Larissa R. Burka,Sharlene Calorossi,Lena Cambron,Guillermo Carbonell,G. Carrara,Christie Chang,Serena Chia-Jen Chang,Steven T. Chen,Esther Cheng,Jonathan Chien,Mashkura Chowdhury,Jonathan H. Chung,Phillip H. Comella,Dana Cosgrove,Francesca Cossarini,Liam Cotter,Arpit Dave,Travis Dawson,Bheesham Dayal,Maxime Dhainaut,R. Dornfeld,Katie Dul,Melody K. Eaton,N. Eber,Cordelia Elaiho,Ethan Ellis,Frank Fabris,Jeremiah J. Faith,Dominique Falci,Susie Feng,Brian Kenneth Fennessy,Marie Correa-Fernandes,N O Fishman,Nancy Francoeur,Sandeep Gangadharan,Daniel Geanon,Bruce D. Gelb,Benjamin S. Glicksberg,Joanna Grabowska,Gavin Gyimesi,Maha El Hamdani,Diana Z. Handler,Jocelyn Harris,Matthew Hartnett,Sandra Hatem,Manon Herbinet,Elva Herrera,Arielle Hochman,Gabriel E. Hoffman,J.L. Hook,L Horta,Etienne Humblin,Suraj K. Jaladanki,Hajra Jamal,Jessica S. Johnson,Gurpawan Kang,Neha Karekar,Subha Karim,Geoffrey Kelly,Jong Kim,Seunghee Kim-Schulze,Edgar Ernesto Gonzalez Kozlova,Arvind Kumar,Josefina Lacunza,Alona Lansky,Dannielle Lebovitch,Brian T. Lee,Grace Lee,Gyu Ho Lee,Jacky Hoong Lee,John Leech,Lauren Lepow,Michael Leventhal,Lora Liharska,Katherine E. Lindblad,Alexandra E. Livanos,Bojan Losic,Rosalie Machado,Kent Madrid,Zafar Mahmood,Kelcey Mar,Thomas U. Marron,Glenn Martin,Robert Marvin,Shrisha Maskey,Paul Matthews,Katherine Meckel,Saurabh Mehandru,Cynthia R. Mercedes,Elyze Merzier,Dara Meyer,Gurkan Mollaoglu,Sarah Morris,Emily Moya,Naa-akomaah Yeboah,Girish N. Nadkarni,Marjorie Nisenholtz,George Ofori-Amanfo,Kenan Onel,Merouane Ounadjela,Manishkumar Dasharathalal Patel,V. Patel,Cassandra Pruitt,Adeeb Rahman,S. Rathi,Jamie L Redes,Ivan Reyes-Torres,Alcina A. Rodrigues,Alfonso Rodriguez,Vladimir Roudko,Panagiotis Roussos,Evelyn Henao Ruiz,Pearl Scalzo,Robert Sebra,Hardik Shah,Mark M. Shervey,Pedro Silva,Melissa Smith,Alessandra Soares Schanoski,Juan C. Diaz Soto,Shwetha Hara Sridhar,Stacey Brown,Hiyab Stefanos,Meghan Straw,Robert Sweeney,Alexandra Tabachnikova,Collin D. Teague,Manying Tin,Kevin Tuballes,Scott R. Tyler,Bhaskar Upadhyaya,Akhil Vaid,Verena van der Heide,Natalie Vaninov,Konstantinos Vlachos,Daniel Wacker,Laura Walker,Hadley Walsh,Wenhui Wang,Bo Wang,Christian Matthias Wilk,Lillian Wilkins,Karen Wilson,Jessica A. Wilson,Lifei Xue,Nancy Yi,Ying-Chih Wang,Mahlet Yishak,S. Young,Alex Eunkyeong Yu,Nina Zaks,Ren-Yuan Zha,Celia M. T. Greenwood,CJ Paterson,Michael A Hinterberg,Claudia Langenberg,Vincenzo Forgetta,Vincent Mooser,Noam D. Beckmann,Ephraim Kenigsberg,Alexander W. Charney,Miriam Merad,Daniel Kaufmann,Sacha Gnjatic,J. Brent Richards +227 more
TL;DR: In this article , the authors measured 147 immune-related proteins during acute COVID-19 to investigate the differences in outcomes between sexes between severe cases and controls, adjusting for age and sex.
Journal ArticleDOI
Circulating proteins to predict COVID-19 severity.
Chen-Yang Su,Sirui Zhou,Edgar Gonzalez-Kozlova,Guillaume Butler-Laporte,Elsa Brunet-Ratnasingham,Tomoko Nakanishi,Wonseok Jeon,David R. Morrison,Lætitia Laurent,Jonathan Afilalo,Marc Afilalo,D. Henry,Yiheng Chen,Julia Carrasco-Zanini,Yossi Farjoun,Maik Pietzner,N. A. Kimchi,Zaman Afrasiabi,Nardin Rezk,M. Bouab,Louis Petitjean,Charlotte Guzman,Xiaoqing Xue,Chris Tselios,Branka Vulesevic,Olumide Adeleye,Tala Abdullah,Noor Almamlouk,Yara Moussa,Chantal DeLuca,N Duggan,Erwin Schurr,Nathalie Brassard,Madeleine Durand,Diane Marie Del Valle,Ryan F. Thompson,Mario A. Cedillo,Eric E. Schadt,Kai Nie,Nicole W. Simons,Konstantinos Mouskas,Nicolas Zaki,Manishkumar Dasharathalal Patel,Hui Xie,Jocelyn Harris,Robert Marvin,Esther Cheng,Kevin Tuballes,Kimberly Argueta,Ieisha Scott,Celia M. T. Greenwood,Clare Paterson,Michael A Hinterberg,Claudia Langenberg,Vincenzo Forgetta,J. Pineau,Vincent Mooser,Thomas U. Marron,Noam D. Beckmann,Seunghee Kim-Schulze,Alexander W. Charney,Sacha Gnjatic,Daniel Kaufmann,Miriam Merad,J. Brent Richards +64 more
TL;DR: In this paper , the authors measured 4701 circulating human protein abundances in two independent cohorts totaling 986 individuals and trained prediction models including protein abundance and clinical risk factors to predict COVID-19 severity.