H. Shelton Earp

TL;DR: Basal-like breast tumors occurred at a higher prevalence among premenopausal African American patients compared with postmenopausal American and non-African American patients in this population-based study, and their associations with tumor size, axillary nodal status, mitotic index, nuclear pleomorphism, combined grade, p53 mutation status, and breast cancer-specific survival were examined.

TL;DR: The Mer receptor tyrosine kinase seems to be critical for the engulfment and efficient clearance of apoptotic cells, which has implications for inflammation and autoimmune diseases such as systemic lupus erythematosus.

TL;DR: In the Carolina Breast Cancer Study, a population-based, case-control study of African-American and white women, the authors found that up to 68% of basal-like breast cancer could be prevented by promoting breastfeeding and reducing abdominal adiposity as mentioned in this paper.

TL;DR: The inhibitor-induced RTK profile suggested a kinase inhibitor combination therapy that produced GEMM tumor apoptosis and regression where single agents were ineffective, allowing rational design of combination therapies for cancer.

TL;DR: A comprehensive review of the structure, regulation, biologic functions, and downstream signaling pathways of the TAM family of receptor tyrosine kinases and recent evidence suggests a role for TAM receptors in oncogenic mechanisms.