H
Hai-Li Ma
Researcher at Chinese Academy of Sciences
Publications - 7
Citations - 1987
Hai-Li Ma is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: AMP-activated protein kinase & AMPK. The author has an hindex of 4, co-authored 4 publications receiving 1174 citations. Previous affiliations of Hai-Li Ma include Beijing Institute of Genomics.
Papers
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Journal ArticleDOI
Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
Wen Xiao,Samir Adhikari,Samir Adhikari,Ujwal Dahal,Ujwal Dahal,Yu-Sheng Chen,Yu-Sheng Chen,Ya-Juan Hao,Ya-Juan Hao,Bao-Fa Sun,Hui-Ying Sun,Hui-Ying Sun,Ang Li,Ang Li,Xiao-Li Ping,Weiyi Lai,Xing Wang,Xing Wang,Hai-Li Ma,Hai-Li Ma,Chun-Min Huang,Ying Yang,Niu Huang,Guibin Jiang,Hailin Wang,Qi Zhou,Xiu-Jie Wang,Yong-Liang Zhao,Yun-Gui Yang,Yun-Gui Yang +29 more
TL;DR: The findings provide the direct evidence that m(6)A reader YTHDC1 regulates mRNA splicing through recruiting and modulating pre-mRNA splicing factors for their access to the binding regions of targeted mRNAs.
Journal ArticleDOI
5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m 5 C reader
Xin Yang,Ying Yang,Bao-Fa Sun,Yu-Sheng Chen,Yu-Sheng Chen,Jia-Wei Xu,Jia-Wei Xu,Weiyi Lai,Ang Li,Ang Li,Xing Wang,Xing Wang,Devi Prasad Bhattarai,Devi Prasad Bhattarai,Wen Xiao,Sun Huiying,Qin Zhu,Qin Zhu,Hai-Li Ma,Hai-Li Ma,Samir Adhikari,Min Sun,Ya-Juan Hao,Bing Zhang,Chun-Min Huang,Niu Huang,Guibin Jiang,Yong-Liang Zhao,Hailin Wang,Ying-Pu Sun,Yun-Gui Yang,Yun-Gui Yang +31 more
TL;DR: It is revealed that m5C modification is enriched in CG-rich regions and in regions immediately downstream of translation initiation sites and has conserved, tissue-specific and dynamic features across mammalian transcriptomes.
Journal ArticleDOI
RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay.
Ying Yang,Lu Wang,Xiao Han,Wen-Lan Yang,Wen-Lan Yang,Mengmeng Zhang,Hai-Li Ma,Bao-Fa Sun,Ang Li,Ang Li,Jun Xia,Jing Chen,Jing Chen,Jian Heng,Baixing Wu,Yu-Sheng Chen,Yu-Sheng Chen,Jia-Wei Xu,Xin Yang,Xin Yang,Huan Yao,Huan Yao,Jiawei Sun,Cong Lyu,Hailin Wang,Ying Huang,Ying-Pu Sun,Yongliang Zhao,Anming Meng,Jinbiao Ma,Feng Liu,Yun-Gui Yang +31 more
TL;DR: This study discovered that Y-box binding protein 1 (Ybx1) preferentially recognizes m5C-modified mRNAs through π-π interactions with a key residue, Trp45, in YbX1's cold shock domain (CSD), which plays essential roles in maternal mRNA stability and early embryogenesis of zebrafish.
Book ChapterDOI
5-Methylcytosine Analysis by RNA-BisSeq
TL;DR: An optimized RNA-BisSeq method is introduced by using ACT random hexamers to prime the reverse transcription of bisulfite-treated RNA samples to detect the m5C sites.
Journal ArticleDOI
Activated AMP-activated protein kinase prevents hepatic steatosis, oxidative stress and inflammation in primary chicken hepatocytes
TL;DR: AMS-activated protein kinase acts as a potential target for the prevention of fatty liver hemorrhagic syndrome occurrence in laying hens and the beneficial effects of AMP-activatedprotein kinase signal in relieving lipid metabolism disorders, oxidative stress and inflammatory response are found.