H
Hajo Delius
Researcher at German Cancer Research Center
Publications - 61
Citations - 8794
Hajo Delius is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Gene & Virus. The author has an hindex of 39, co-authored 61 publications receiving 8512 citations. Previous affiliations of Hajo Delius include Uppsala University & Max Planck Society.
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Journal ArticleDOI
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
TL;DR: Dkk-1 is a potent antagonist of Wnt signalling, suggesting that dkk genes encode a family of secreted Wnt inhibitors.
Journal ArticleDOI
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.
Bingyu Mao,Wei Wu,Gary Davidson,Joachim Marhold,Mingfa Li,Bernard M. Mechler,Hajo Delius,Dana Hoppe,Peter Stannek,Carmen Walter,Andrei Glinka,Christof Niehrs +11 more
TL;DR: Kremen1 and Kremen2 are components of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates that functionally cooperate with Dkk1 to block Wnt/β-catenin signalling.
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Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.
Darya Onichtchouk,Ye Guang Chen,Roland Dosch,Volker Gawantka,Hajo Delius,Joan Massagué,Christof Niehrs +6 more
TL;DR: The results indicate that BAMBI negatively regulates TGF-β-family signalling by a regulatory mechanism involving the interaction of signalling receptors with a pseudoreceptor and prevents the formation of receptor complexes.
Journal ArticleDOI
Identification and Assessment Of Known And Novel Human Papillomaviruses by Polymerase Chain Reaction Amplification, Restriction Fragment Length Polymorphisms, Nucleotide Sequence, and Phylogenetic Algorithms
Hans-Ulrich Bernard,Shih-Yen Chan,M. Michele Manos,Chi-Keong Ong,Luisa L. Villa,Hajo Delius,Cheri L. Peyton,Heidi M. Bauer,Cosette M. Wheeler +8 more
TL;DR: Methods and corresponding DNA sequence data bases were designed for the reliable identification of mucosal HPV genomes from clinical specimens and 10 PCR fragments were identified that would qualify as new genital HPV types after complete genomic isolation.
Journal ArticleDOI
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Mark Johnston,LaDeana W. Hillier,Linda Riles,K. Albermann,Brigitte André,W. Ansorge,V. Benes,M. Bruckner,Hajo Delius,E. Dubois,A. Düsterhöft,Kd. Entian,M. Floeth,André Goffeau,U. Hebling,K. Heumann,D. Heussneitzel,H. Hilbert,F. Hilger,K. Kleine,Peter Kötter,Edward J. Louis,F. Messenguy,Hw. Mewes,T. Miosga,D. Mostl,S. Mullerauer,U. Nentwich,B. Obermaier,E. Piravandi,Tm. Pohl,Daniel Portetelle,Bénédicte Purnelle,S. Rechmann,Michael A. Rieger,M. Rinke,Matthias Rose,M. Scharfe,B. Scherens,P. Scholler,Christian Schwager,S. Schwarz,Ap. Underwood,La. Urrestarazu,Micheline Vandenbol,P. Verhasselt,F. Vierendeels,M. Voet,G. Volckaert,H. Voss,R. Wambutt,E. Wedler,H. Wedler,Fk. Zimmermann,A. Zollner,J. Hani,Jd. Hoheisel +56 more
TL;DR: No correlation was found between G+C content and gene density along the chromosome, and their variations are random, so accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.