H
Han Fei Ding
Researcher at Georgia Regents University
Publications - 91
Citations - 4803
Han Fei Ding is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Neuroblastoma & Apoptosis. The author has an hindex of 36, co-authored 80 publications receiving 3936 citations. Previous affiliations of Han Fei Ding include Charlie Norwood VA Medical Center & University of South Alabama.
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Journal ArticleDOI
Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability
Gaël McGill,Martin A. Horstmann,Hans R. Widlund,Jinyan Du,Gabriela Motyckova,Emi K. Nishimura,Yi Ling Lin,Sridhar Ramaswamy,Sridhar Ramaswamy,William Avery,Han Fei Ding,Siobhán A. Jordan,Ian J. Jackson,Stanley J. Korsmeyer,Todd R. Golub,Todd R. Golub,David E. Fisher +16 more
TL;DR: Clinically, primary human melanoma expression microarrays revealed tight nearest neighbor linkage for MITF and BCL2, which helps explain the vital roles of both Mitf and Bcl2 in the melanocyte lineage and the well-known treatment resistance of melanoma.
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ATF3 promotes erastin-induced ferroptosis by suppressing system Xc
Liyuan Wang,Liyuan Wang,Yichen Liu,Tingting Du,Tingting Du,Heng Yang,Lei Lei,Mengqi Guo,Han Fei Ding,Junran Zhang,Hongbo Wang,Xiaoguang Chen,Chunhong Yan +12 more
TL;DR: It is reported that activating transcription factor 3 (ATF3), a common stress sensor, can promote ferroptosis induced by erastin and add ATF3 to a short list of proteins that can regulate system Xc− and promote feroptosis repressed by this antiporter.
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Lineage-specific Signaling in Melanocytes c-Kit STIMULATION RECRUITS p300/CBP TO MICROPHTHALMIA
E. Roydon Price,Han Fei Ding,Tina M. Badalian,Shoumo Bhattacharya,Clifford M. Takemoto,Tso-Pang Yao,Timothy J. Hemesath,David E. Fisher +7 more
TL;DR: The transcriptional coactivator p300/CBP selectively associates with mitogen-activated protein kinase-phosphorylated Mi, even under conditions in which non-MAPK phospho-Mi is more abundant.
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The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation
Jane Ding,Tai Li,Tai Li,Xiangwei Wang,Erhu Zhao,Erhu Zhao,Jeong Hyeon Choi,Liqun Yang,Yunhong Zha,Zheng Dong,Shuang Huang,John M. Asara,Hongjuan Cui,Han Fei Ding +13 more
TL;DR: It is shown that the histone H3 lysine 9 (H3K9) methyltransferase G9A is required for maintaining the pathway enzyme genes in an active state marked by H3K 9 monomethylation and for the transcriptional activation of this pathway in response to serine deprivation.
Journal ArticleDOI
Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction
Man J. Livingston,Han Fei Ding,Shuang Huang,Joseph A. Hill,Xiao Ming Yin,Zheng Dong,Zheng Dong +6 more
TL;DR: It is suggested that persistent activation of autophagy in kidney proximal tubules promotes renal interstitial fibrosis during UUO.