H
Hans Wolff
Researcher at Ludwig Maximilian University of Munich
Publications - 105
Citations - 2950
Hans Wolff is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Semen & Alopecia areata. The author has an hindex of 27, co-authored 104 publications receiving 2689 citations. Previous affiliations of Hans Wolff include Brigham and Women's Hospital & University of Düsseldorf.
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Journal ArticleDOI
The biologic significance of white blood cells in semen.
Edward E. Wallach,Hans Wolff +1 more
TL;DR: There is ample evidence that WBC can affect sperm function and further studies are needed to define cofactors that increase or decrease the risk of sperm damage by WBC.
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Leukocytospermia is associated with poor semen quality
Hans Wolff,Joseph A. Politch,Adriana Martinez,Florina Haimovici,Joseph A. Hill,Deborah J. Anderson +5 more
TL;DR: In this article, sperm samples from 179 male infertility patients were analyzed for type and number of white blood cells (WBC) by a combination of immunologic techniques and showed that elevated levels of WBC in semen are associated with poor semen quality.
Journal ArticleDOI
Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia
Guntram Bezold,Joseph A. Politch,Joseph A. Politch,Nancy B. Kiviat,Jane Kuypers,Hans Wolff,Deborah J. Anderson,Deborah J. Anderson +7 more
TL;DR: The DNA of STI pathogens was detected in semen from a high percentage of asymptomatic male infertility patients, and was associated with poor semen quality, and efforts to diagnose and treat subclinical genital-tract infections should be intensified.
Journal ArticleDOI
Immunohistologic characterization and quantitation of leukocyte subpopulations in human semen
Hans Wolff,Deborah J. Anderson +1 more
TL;DR: When the immunoperoxidase technique was applied to semen smears from 17 proven fertile men and 51 randomly selected infertility patients, the authors found highly varying total leukocyte numbers, ranging from 8970 to 20,520,000 per ejaculate among fertile men (median, 170,000), and from 43,120 to 104,580,000 among infertility patients (Median, 1,035,000).
Journal ArticleDOI
Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci
Regina C. Betz,Lynn Petukhova,Stephan Ripke,Stephan Ripke,Hailiang Huang,Hailiang Huang,Androniki Menelaou,Silke Redler,Tim Becker,Tim Becker,Stefanie Heilmann,Tarek Yamany,Madeliene Duvic,Maria K. Hordinsky,David A. Norris,Vera H. Price,Julian Mackay-Wiggan,Annemieke de Jong,Gina M. DeStefano,Susanne Moebus,Markus Böhm,Ulrike Blume-Peytavi,Hans Wolff,Gerhard Lutz,Roland Kruse,Li Bian,Christopher I. Amos,Annette Lee,Peter K. Gregersen,Bettina Blaumeiser,David Altshuler,David Altshuler,Raphael Clynes,Paul I.W. de Bakker,Markus M. Nöthen,Mark J. Daly,Mark J. Daly,Angela M. Christiano +37 more
TL;DR: The first meta-analysis in AA is performed by combining data from two genome-wide association studies (GWAS), and replication with supplemented ImmunoChip data for a total of 3,253 cases and 7,543 controls, finding new molecular pathways disrupted in AA that support the causal role of aberrant immune processes in AA.