Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia
Guntram Bezold,Joseph A. Politch,Joseph A. Politch,Nancy B. Kiviat,Jane Kuypers,Hans Wolff,Deborah J. Anderson,Deborah J. Anderson +7 more
TLDR
The DNA of STI pathogens was detected in semen from a high percentage of asymptomatic male infertility patients, and was associated with poor semen quality, and efforts to diagnose and treat subclinical genital-tract infections should be intensified.About:
This article is published in Fertility and Sterility.The article was published on 2007-05-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Male infertility & Semen quality.read more
Citations
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Oxidative stress and male infertility—a clinical perspective
TL;DR: This review will provide an overview of oxidative biochemistry related to sperm health and identify which men are most at risk of oxidative infertility, and outline methods available for diagnosing oxidative stress and the various treatments available.
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Seminal Fluid Induces Leukocyte Recruitment and Cytokine and Chemokine mRNA Expression in the Human Cervix after Coitus
David J. Sharkey,Kelton Tremellen,Melinda J. Jasper,Kristina Gemzell-Danielsson,Sarah A. Robertson +4 more
TL;DR: The leukocyte and cytokine environment induced in the cervix by seminal fluid appears competent to initiate adaptations in the female immune response that promote fertility and is also relevant to transmission of sexually transmitted pathogens and potentially, susceptibility to cervical metaplasia.
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Genital tract infections and infertility.
Donatella Pellati,Ioannis Mylonakis,Giulio Bertoloni,Cristina Fiore,Alessandra Andrisani,Guido Ambrosini,Decio Armanini +6 more
TL;DR: The role of infections, particularly co-infections, as causes of the impairment of sperm quality, motility and function needs further investigation.
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Review of cytomegalovirus shedding in bodily fluids and relevance to congenital cytomegalovirus infection.
TL;DR: In this article, the authors reviewed studies of CMV shedding in bodily fluids (defined as CMV detected by culture or CMV DNA detected by polymerase chain reaction) and found that children with congenital cytomegalovirus (CMV) infection exhibited the highest prevalences of shedding, with a steep decline by age five, indicating that young children are the key transmission risk for pregnant women.
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2015 European guideline on the management of Chlamydia trachomatis infections
TL;DR: Up-to-date guidance regarding broader indications for testing and treatment of C. trachomatis infections is provided and the recommendation of increased testing to reduce the incidence of pelvic inflammatory disease and prevent exposure to infection is recommended.
References
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Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
Randall Keichi Saiki,David H. Gelfand,Susanne Stoffel,Stephen J. Scharf,Russell Higuchi,Glenn Thomas Horn,Kary B. Mullis,Henry A. Erlich +7 more
TL;DR: A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction, which significantly improves the specificity, yield, sensitivity, and length of products that can be amplified.
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A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.
TL;DR: The complete recovery of DNA from samples used for the RNA and protein isolation makes it possible to normalize the results of gene expression studies based on DNA content instead of on the more variable total RNA, protein content or tissue weight.
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Viral hepatitis B
TL;DR: Current available monotherapies-interferon, lamivudine, and adefovir dipivoxil-very rarely eradicate the virus, but greatly reduce its replication, necroinflammatory histological activity, and progression of fibrosis.
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Epstein-Barr Virus Infection
TL;DR: The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr and has been found in tissues from other cancers, including T-cell lymphomas and Hodgkin's disease.
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Identification of human herpesvirus-6 as a causal agent for exanthem subitum
Koichi Yamanishi,Kimiyasu Shiraki,Toshio Kondo,Toshiomi Okuno,Michiaki Takahashi,Yoshizo Asano,Takeshi Kurata +6 more
TL;DR: The results strongly suggest that the newly isolated virus is identical or closely related to HHV-6 and the causal agent for exanthem subitum.