H
Harry B. Greenberg
Researcher at Stanford University
Publications - 441
Citations - 36848
Harry B. Greenberg is an academic researcher from Stanford University. The author has contributed to research in topics: Rotavirus & Virus. The author has an hindex of 100, co-authored 433 publications receiving 34941 citations. Previous affiliations of Harry B. Greenberg include Baylor College of Medicine & United States Department of Commerce.
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Journal ArticleDOI
Helicobacter pylori in Peptic Ulcer Disease
Tadataka Yamada,John G. Searle,Dennis J. Ahnen,David H. Aipers,Harry B. Greenberg,Martha Gray,Kent B. Joscelyn,Kent B. McNair,Kent B. Jeffrey,Gordon Kauffman,Daniel K. Podolsky,Wayne A. Ray,Dennis R. Schaberg,Fred E. Silverstein,Michael V. Sivak,Ann L.B. Williams,Robert H. Yolken,Martin J. Blaser,Geron Borsch,Pelayo Correa,Steven J. Czinn,David Forman,David Y. Graham,Jon L. Isenberg,Dennis M. Jensen,Barry J. Marshall,Julie Parsonnet,Walter L. Peterson,Pentti Sipponen,Duane T. Smoot,Andrew H. Soil,Amnon Sonnenberg,Nicholas J. Talley,W. Grant Thompson,Guido N. J. Tytgat,John H. Walsh,T. Ulf Westblom,Kenneth G. Wormsley,Frank A. Hamilton,Addison B. Scoville,Benjamin T. Burton,Leslie Curtis,Jerry M. Elliott,James E. Everhart,John H. Ferguson,Willis R. Foster,William H. Hall,Jay H. Hoofnagle,Leslye D. Johnson,John Walsh,Phillip Gorden,Anthony S. Fauci +51 more
TL;DR: It is concluded that ulcer patients with H. pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence.
Journal ArticleDOI
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.
Ruochen Zang,Ruochen Zang,Maria Florencia Gomez Castro,Broc T. McCune,Qiru Zeng,Paul W. Rothlauf,Paul W. Rothlauf,Naomi M. Sonnek,Zhuoming Liu,Kevin Brulois,Kevin Brulois,Xin Wang,Harry B. Greenberg,Harry B. Greenberg,Michael S. Diamond,Matthew A. Ciorba,Sean P. J. Whelan,Siyuan Ding +17 more
TL;DR: In this article, the authors reported productive infection of SARS-CoV-2 in ACE2+ mature enterocytes in human small intestinal enteroids, which may contribute to local and systemic illness and overall disease progression.
Journal ArticleDOI
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Zhenyu Zhong,Shuang Liang,Elsa Sanchez-Lopez,Feng He,Shabnam Shalapour,Xue Jia Lin,Xue Jia Lin,Jerry Wong,Siyuan Ding,Siyuan Ding,Ekihiro Seki,Bernd Schnabl,Andrea L. Hevener,Harry B. Greenberg,Harry B. Greenberg,Tatiana Kisseleva,Michael Karin +16 more
TL;DR: It is shown that the synthesis of mitochondrial DNA (mtDNA), induced after the engagement of Toll-like receptors, is crucial for NLRP3 signalling, and the dependence on CMPK2 catalytic activity provides opportunities for more effective control ofNLRP3 inflammasome-associated diseases.
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Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection
Heiner Wedemeyer,Xiao-Song He,Michelina Nascimbeni,Anthony R. Davis,Harry B. Greenberg,Jay H. Hoofnagle,T. Jake Liang,Harvey J. Alter,Barbara Rehermann +8 more
TL;DR: The defective functions of HCV-specific CD8+ T cells might contribute to viral persistence in chronically infected patients, and knowledge on their reversibility may facilitate the development of immunotherapeutic vaccines.
Journal ArticleDOI
Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity.
Eric J. Kunkel,James Campbell,Guttorm Haraldsen,Junliang Pan,Judie Boisvert,Arthur I. Roberts,Ellen C. Ebert,Mark A. Vierra,Stuart B. Goodman,Mark C. Genovese,Andrew J. Wardlaw,Harry B. Greenberg,Christina M. Parker,Eugene C. Butcher,David P. Andrew,William W. Agace +15 more
TL;DR: Results imply a restricted role for lymphocyte CCR9 and its ligand TECK in the small intestine, and provide the first evidence for distinctive mechanisms of lymphocyte recruitment that may permit functional specialization of immune responses in different segments of the gastrointestinal tract.