Harry B. Greenberg

TL;DR: Stool specimens from infants with rotavirus gastroenteritis hospitalized in two Mexican cities were examined by serotype- and subgroup-specific enzyme immunoassays and indicate that heterotypic neutralizing antibody responses occur frequently following infection with serotype 4 rotaviruses.

TL;DR: RV-specific B cell repertoires of infants aged 2–11 mo and those of adults were highly related when compared by VH, D, JH, VL, and JL segment selection, extent of junctional diversity, and mean H chain complementarity determining region 3 length, suggesting that residual fetal bias of the B cell repertoire is not a limiting determinant of the quality of Ab responses to viruses beyond the neonatal period.

TL;DR: Serum levels of both antigen and RNA were inversely associated with baseline titers of rotaviral serum immunoglobulin G, andAntigenemia was associated with infection with G1 strains and with low baseline titer of rotviral serum antibody.

TL;DR: The 116E strain is attenuated, clinically safe and highly immunogenic with a single dose of rotavirus vaccine candidates 116E and I321 and there were no significant differences in the number of adverse events.

TL;DR: The results highlight the intestine as a potential site of SARS-CoV-2 replication, which may contribute to local and systemic illness and overall disease progression.