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Helen Cho

Researcher at University of Medicine and Dentistry of New Jersey

Publications -  17
Citations -  3042

Helen Cho is an academic researcher from University of Medicine and Dentistry of New Jersey. The author has contributed to research in topics: RNA polymerase II & RNA polymerase II holoenzyme. The author has an hindex of 17, co-authored 17 publications receiving 2817 citations. Previous affiliations of Helen Cho include Rutgers University & Howard Hughes Medical Institute.

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A human RNA polymerase II complex associated with SRB and DNA-repair proteins

TL;DR: In this article, the isolation of a human RNA polymerase II complex containing a subset of the basal transcription factors and the human homologues of the yeast SRB proteins was reported.
Journal Article

A Human RNA-Polymerase-II Complex-Associated with SRB and DNA-Repair Proteins (Vol 381, Pg 86, 1996)

TL;DR: The isolation of a humanRNA polymerase II complex containing a subset of the basal transcription factors and the human homologues of the yeast SRB (for suppressors of RNA polymerase B) proteins1–3 is reported.
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A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure

TL;DR: Protein interaction studies demonstrate a direct interaction between RNA polymerase II and the histone acetyltransferases p300 and PCAF, and p300 interacts specifically with the nonphosphorylated, initiation-competent form of RNA polymerases II.
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The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

TL;DR: Binding of Spt6 to Ser2-P RNAPII provides a cotranscriptional mechanism to recruit Iws1, REF1/Aly, and associated mRNA processing, surveillance, and export factors to responsive genes.