H
Henry Engler
Researcher at University of the Republic
Publications - 69
Citations - 7701
Henry Engler is an academic researcher from University of the Republic. The author has contributed to research in topics: Astrocytosis & PET-CT. The author has an hindex of 24, co-authored 67 publications receiving 7159 citations. Previous affiliations of Henry Engler include Uppsala University Hospital & Uppsala University.
Papers
More filters
Journal ArticleDOI
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.
William E. Klunk,Henry Engler,Agneta Nordberg,Yanming Wang,G. Blomqvist,Daniel P. Holt,Mats Bergström,Irina Savitcheva,Guo Feng Huang,Sergio Estrada,Birgitta Ausén,Manik L. Debnath,Julien Barletta,Julie C. Price,Johan Sandell,Brian J. Lopresti,Anders Wall,Pernilla Koivisto,Gunnar Antoni,Chester A. Mathis,Bengt Långström +20 more
TL;DR: The results suggest that PET imaging with the novel tracer, PIB, can provide quantitative information on amyloid deposits in living subjects.
Journal ArticleDOI
PET imaging of amyloid deposition in patients with mild cognitive impairment
Anton Forsberg,Henry Engler,Ove Almkvist,Ove Almkvist,Ove Almkvist,Gunnar Blomquist,Göran Hagman,Anders Wall,Anna Ringheim,Bengt Langstrom,Bengt Langstrom,Agneta Nordberg,Agneta Nordberg +12 more
TL;DR: Correlations were observed in the MCI patients between PIB retention and CSF Abeta(1-42), total Tau and episodic memory, respectively, and the P IB retention in MCI converters was comparable to AD patients.
Journal ArticleDOI
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.
Henry Engler,Anton Forsberg,Ove Almkvist,Gunnar Blomquist,Emma Larsson,Irina Savitcheva,Anders Wall,Anna Ringheim,Bengt Långström,Agneta Nordberg +9 more
TL;DR: Relatively stable PIB retention after 2 years of follow-up in patients with mild Alzheimer's disease suggests that amyloid deposition in the brain reaches a plateau by the early clinical stages of Alzheimer’s disease and therefore may precede a decline in rCMRGlc and cognition.
Journal ArticleDOI
Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG
Stephen F. Carter,Michael Schöll,Ove Almkvist,Anders Wall,Henry Engler,Bengt Långström,Agneta Nordberg +6 more
TL;DR: Increased 11C-DED binding throughout the brain of the MCI 11C/PIB+ patients potentially suggests that astrocytosis is an early phenomenon in AD development.
Journal ArticleDOI
In vivo amyloid imaging with PET in frontotemporal dementia.
Henry Engler,Alexander Santillo,Shu Xia Wang,Maria Lindau,Irina Savitcheva,Agneta Nordberg,Agneta Nordberg,Lars Lannfelt,Bengt Langstrom,Bengt Langstrom,Lena Kilander +10 more
TL;DR: PIB could potentially aid in differentiating between FTD and AD, and eight FTD patients showed significantly lower PIB retention compared to AD in frontal, parietal, temporal, temporal and occipital cortices.