H
Hermine Agis
Researcher at Medical University of Vienna
Publications - 120
Citations - 6983
Hermine Agis is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Basophil & Mast cell. The author has an hindex of 33, co-authored 105 publications receiving 6407 citations. Previous affiliations of Hermine Agis include University of Vienna.
Papers
More filters
Journal ArticleDOI
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
Brian J. Druker,François Guilhot,Stephen G. O'Brien,Insa Gathmann,Hagop M. Kantarjian,Norbert Gattermann,Michael W. Deininger,Richard T. Silver,John M. Goldman,Richard Stone,Francisco Cervantes,Andreas Hochhaus,Bayard L. Powell,Janice Gabrilove,Philippe Rousselot,Josy Reiffers,Jan J. Cornelissen,Timothy P. Hughes,Hermine Agis,Thea Kolsen Fischer,Gregor Verhoef,John D. Shepherd,Giuseppe Saglio,Alois Gratwohl,Johan Lanng Nielsen,Jerald P. Radich,Bengt Simonsson,Kerry Taylor,Michele Baccarani,Charlene So,Laurie Letvak,Richard A. Larson +31 more
TL;DR: After 5 years of follow-up, continuous treatment of chronic-phase CML with imatinib as initial therapy was found to induce durable responses in a high proportion of patients.
Journal ArticleDOI
Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture.
Peter Valent,E. Spanblöchl,Wolfgang R. Sperr,Christian Sillaber,Krisztina M. Zsebo,Hermine Agis,Herbert Strobl,Klaus Geissler,Peter Bettelheim,Klaus Lechner +9 more
TL;DR: Observations suggest that rhSCF induces in vitro differentiation of human MCs from their BM and PB precursor cells in long-term culture and upregulates MC releasability.
Journal Article
Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells.
Wolfgang Füreder,Hermine Agis,M. Willheim,H C Bankl,U. Maier,Kazuo Kishi,M.R. Müller,K. Czerwenka,T Radaszkiewicz,Joseph H. Butterfield,G W Klappacher,Wolfgang R. Sperr,M Oppermann,Klaus Lechner,Peter Valent +14 more
TL;DR: Basophils and mast cells express a different profile of complement receptors, and C5a-dependent mediator release in skin mast cells and basophils is mediated via CD88, which shows that mast cells constitute a heterogeneous lineage in terms of expression of the C 5a binding site CD88.
Journal ArticleDOI
Comparative immunophenotypic analysis of human mast cells, blood basophils and monocytes
Hermine Agis,Wolfgang Füreder,Hans Bankl,Michael Kundi,W. R. Sperr,Martin Willheim,George Boltz-Nitulescu,Joseph H. Butterfield,Kazuo Kishi,Klaus Lechner,Peter Valent +10 more
TL;DR: MC, Ba and Mo display a unique CD profile with MC being the most distantly related cell and the most significant mismatch within a given lineage is the loss of cytokine R on mature MC as compared with normal myeloid progenitors and HMC‐1 cells.
Journal ArticleDOI
The human cardiac mast cell: localization, isolation, phenotype, and functional characterization
Wolfgang R. Sperr,Hans Bankl,Gerald Mundigler,Günter Klappacher,Karl Grossschmidt,Hermine Agis,Paul Simon,P Laufer,M. Imhof,T. Radaszkiewicz,Dietmar Glogar,Klaus Lechner,Peter Valent +12 more
TL;DR: The human cardiac mast cell (CMC) is an MCTC primarily located in the appendage of the atrium and exhibits surface membrane antigen and functional properties similar to those of lung and uterus MC.