H
Hervé Hogues
Researcher at National Research Council
Publications - 24
Citations - 2279
Hervé Hogues is an academic researcher from National Research Council. The author has contributed to research in topics: Candida albicans & Gene. The author has an hindex of 17, co-authored 24 publications receiving 2128 citations.
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Journal ArticleDOI
Transcription Profiling of Candida albicans Cells Undergoing the Yeast-to-Hyphal Transition
André Nantel,Daniel Dignard,Catherine Bachewich,Doreen Harcus,Anne Marcil,Anne-Pascale Bouin,Christoph Wilhelm Sensen,Hervé Hogues,Marco van het Hoog,Paul M. K. Gordon,Tracey Rigby,François Benoit,Daniel C. Tessier,David Y. Thomas,Malcolm Whiteway +14 more
TL;DR: Glass DNA microarrays used to investigate the transcription profiles of 6333 predicted ORFs in cells undergoing this transition and their responses to changes in temperature and culture medium identified transcripts that are induced before germ tube initiation and shut off later in the developmental process.
Journal ArticleDOI
A Human-Curated Annotation of the Candida albicans Genome
Burkhard R. Braun,Marco van het Hoog,Christophe d'Enfert,Mikhail Martchenko,Jan Dungan,Alan Kuo,Diane O. Inglis,M. Andrew Uhl,Hervé Hogues,Matthew Berriman,Michael C. Lorenz,Anastasia Levitin,Ursula Oberholzer,Catherine Bachewich,Doreen Harcus,Anne Marcil,Daniel Dignard,Tatiana Iouk,Rosa Zito,Lionel Frangeul,Fredj Tekaia,Kim Rutherford,Edwin Wang,Carol A. Munro,Steve Bates,Neil A. R. Gow,Lois L. Hoyer,Gerwald A. Köhler,Joachim Morschhäuser,George Newport,Sadri Znaidi,Martine Raymond,Bernard Turcotte,Gavin Sherlock,Maria C. Costanzo,Jan Ihmels,Judith Berman,Dominique Sanglard,Nina Agabian,Aaron P. Mitchell,Alexander D. Johnson,Malcolm Whiteway,André Nantel +42 more
TL;DR: Improved annotation permitted a detailed analysis of several multigene families, and comparative genomic studies showed that C. albicans has a far greater catabolic range, encoding respiratory Complex 1, several novel oxidoreductases and ketone body degrading enzymes, malonyl- CoA and enoyl-CoA carriers, and numerous transporters to assimilate the resulting nutrients.
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The functional potential of high Arctic permafrost revealed by metagenomic sequencing, qPCR and microarray analyses.
TL;DR: The detailed functional potential of permafrost-affected soils is described for the first time and key genes related to methane generation, methane oxidation and organic matter degradation were highly diverse for both samples in the metagenomic libraries and some showed relatively high abundance in qPCR assays.
Journal ArticleDOI
Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans.
Christopher Askew,Adnane Sellam,Adnane Sellam,Elias Epp,Elias Epp,Hervé Hogues,Alaka Mullick,Alaka Mullick,André Nantel,André Nantel,Malcolm Whiteway,Malcolm Whiteway +11 more
TL;DR: It is suggested that Tye7p represents the key transcriptional regulator of carbohydrate metabolism in C. albicans and Gal4p provides a carbon source-dependent fine-tuning of gene expression while regulating the metabolic flux between respiration and fermentation pathways.
Journal ArticleDOI
Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes
Marco van het Hoog,Timothy J. Rast,Mikhail Martchenko,Suzanne Grindle,Daniel Dignard,Hervé Hogues,Christine Cuomo,Matthew Berriman,Stewart Scherer,B. B. Magee,Malcolm Whiteway,Hiroji Chibana,André Nantel,P. T. Magee +13 more
TL;DR: Assembly 21 reveals an ancient chromosome fusion, a number of small internal duplications followed by inversions, and a subtelomeric arrangement, including a new gene family, the TLO genes, in Candida albicans.