Jan Dungan

TL;DR: Computational methods are developed to assemble a diploid genome sequence in good agreement with available physical mapping data and provide a whole-genome description of heterozygosity in the organism.

TL;DR: Improved annotation permitted a detailed analysis of several multigene families, and comparative genomic studies showed that C. albicans has a far greater catabolic range, encoding respiratory Complex 1, several novel oxidoreductases and ketone body degrading enzymes, malonyl- CoA and enoyl-CoA carriers, and numerous transporters to assimilate the resulting nutrients.

TL;DR: Using a custom Affymetrix GeneChip© representing the entire Candida albicans genome, the changes in genome‐wide gene expression in this opportunistic pathogen are examined as a function of alterations in environmental concentrations of iron to expand the understanding of global iron regulation in C. al bicans and provide insights into the potential role of iron availability.

TL;DR: The mechanism of site-specific genetic recombination mediated by Tn3 resolvase has been investigated by a topological approach and the structure of the knot was as predicted, providing strong evidence for the model and showing the power of the topological method.

TL;DR: A potential alternative pathway for cysteine metabolism and the biofilm-associated expression of genes involved in glutathione production in C. albicans is identified.