H
Hideki Shibata
Researcher at Nagoya University
Publications - 80
Citations - 3372
Hideki Shibata is an academic researcher from Nagoya University. The author has contributed to research in topics: ESCRT & Calcium-binding protein. The author has an hindex of 32, co-authored 78 publications receiving 3064 citations. Previous affiliations of Hideki Shibata include Kobe University.
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Journal ArticleDOI
Characterization of a Novel Giant Scaffolding Protein, CG-NAP, That Anchors Multiple Signaling Enzymes to Centrosome and the Golgi Apparatus
Mikiko Takahashi,Hideki Shibata,Masaki Shimakawa,Masaaki Miyamoto,Hideyuki Mukai,Yoshitaka Ono +5 more
TL;DR: Data indicate that CG-NAP serves as a novel scaffolding protein that assembles several protein kinases and phosphatases on centrosome and the Golgi apparatus, where physiological events, such as cell cycle progression and intracellular membrane traffic, may be regulated by phosphorylation state of specific protein substrates.
Journal ArticleDOI
The ALG-2-interacting Protein Alix Associates with CHMP4b, a Human Homologue of Yeast Snf7 That Is Involved in Multivesicular Body Sorting
Keiichi Katoh,Hideki Shibata,Hidenori Suzuki,Atsuki Nara,Kazumi Ishidoh,Eiki Kominami,Tamotsu Yoshimori,Masatoshi Maki +7 more
TL;DR: Results suggest that CHMP4b and Alix participate in formation of multivesicular bodies by cooperating with SKD1.
Journal ArticleDOI
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.
Bradley N. Smith,Simon Topp,Claudia Fallini,Hideki Shibata,Han-Jou Chen,Claire Troakes,Andrew P. King,Nicola Ticozzi,Kevin P. Kenna,Athina Soragia-Gkazi,Jack W. Miller,Akane Sato,Diana Marques Dias,Maryangel Jeon,Caroline Vance,Chun Hao Wong,Martina de Majo,Wejdan Kattuah,Jacqueline C. Mitchell,Emma L. Scotter,Nicholas W Parkin,Peter C. Sapp,Matthew Nolan,Peter J. Nestor,Michael A. Simpson,Michael E. Weale,Monkel Lek,Monkel Lek,Frank Baas,J M Vianney de Jong,Anneloor L.M.A. ten Asbroek,Alberto Garcia Redondo,Jesús Esteban-Pérez,Cinzia Tiloca,Federico Verde,Stefano Duga,Nigel Leigh,Hardev Pall,Karen E. Morrison,Ammar Al-Chalabi,Pamela J. Shaw,Janine Kirby,Martin R Turner,Kevin Talbot,Orla Hardiman,Jonathan D. Glass,Jacqueline de Belleroche,Masatoshi Maki,Stephen E. Moss,Christopher C.J. Miller,Cinzia Gellera,Antonia Ratti,Safa Al-Sarraj,Robert H. Brown,Vincenzo Silani,John Landers,Christopher Shaw +56 more
TL;DR: It is concluded that mutations in ANXA11 are associated with ALS and implicate defective intracellular protein trafficking in disease pathogenesis.
Journal ArticleDOI
Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins.
TL;DR: Penta-EF-hand (PEF) proteins comprise a family of Ca(2+)-binding proteins that have five repetitive EF-hand motifs that have common features: dimerization through unpaired C-terminal EF5s, possession of hydrophobic Gly/Pro-rich N- terminal domains, and Ca( 2+)-dependent translocation to membranes.
Journal ArticleDOI
Interaction of PKN with alpha-actinin.
Hideyuki Mukai,Masanao Toshimori,Hideki Shibata,Hiromi Takanaga,Michinori Kitagawa,Masako Miyahara,Masaki Shimakawa,Yoshitaka Ono +7 more
TL;DR: PKN is linked to the cytoskeletal network via a direct association between PKN and α-actinin, and the addition of phosphatidylinositol 4,5-bisphosphate stimulated the binding activity of the full-length α-Actinin with PKN.