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Ammar Al-Chalabi

Researcher at King's College London

Publications -  408
Citations -  39166

Ammar Al-Chalabi is an academic researcher from King's College London. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Population. The author has an hindex of 84, co-authored 354 publications receiving 33218 citations. Previous affiliations of Ammar Al-Chalabi include Griffith University & Harvard University.

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Denise Harold, +86 more
- 01 Oct 2009 - 
TL;DR: A two-stage genome-wide association study of Alzheimer's disease involving over 16,000 individuals, the most powerful AD GWAS to date, produced compelling evidence for association with Alzheimer's Disease in the combined dataset.
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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Jemeen Sreedharan, +20 more
- 21 Mar 2008 - 
TL;DR: The evidence suggests a pathophysiological link between TDP-43 and ALS, and neighboring mutations in a highly conserved region of TARDBP in sporadic and familial ALS cases.
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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance, +23 more
- 27 Feb 2009 - 
TL;DR: A missense mutation in the gene encoding fused in sarcoma (FUS) in a British kindred, linked to ALS6, is identified, which suggests that a common mechanism may underlie motor neuron degeneration.
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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Paul Hollingworth, +177 more
- 01 May 2011 - 
TL;DR: Meta-analyses of all data provided compelling evidence that ABCA7 and the MS4A gene cluster are new Alzheimer's disease susceptibility loci and independent evidence for association for three loci reported by the ADGC, which, when combined, showed genome-wide significance.
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Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.