H
Hisayoshi Igarashi
Researcher at Sapporo Medical University
Publications - 21
Citations - 1196
Hisayoshi Igarashi is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 12, co-authored 21 publications receiving 911 citations. Previous affiliations of Hisayoshi Igarashi include University of Tokyo.
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Journal ArticleDOI
Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis
Kei Mitsuhashi,Katsuhiko Nosho,Yasutaka Sukawa,Yasutaka Matsunaga,Miki Ito,Hiroyoshi Kurihara,Shinichi Kanno,Hisayoshi Igarashi,Takafumi Naito,Yasushi Adachi,Mami Tachibana,Tokuma Tanuma,Hiroyuki Maguchi,Toshiya Shinohara,Tadashi Hasegawa,Masafumi Imamura,Yasutoshi Kimura,Koichi Hirata,Reo Maruyama,Hiromu Suzuki,Kohzoh Imai,Hiroyuki Yamamoto,Yasuhisa Shinomura +22 more
TL;DR: Tumor Fusobacterium species status is independently associated with a worse prognosis of pancreatic cancer, suggesting that FusOBacterium Species may be a prognostic biomarker of pancreatIC cancer.
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Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer
Katsuhiko Nosho,Yasutaka Sukawa,Yasushi Adachi,Miki Ito,Kei Mitsuhashi,Hiroyoshi Kurihara,Shinichi Kanno,Itaru Yamamoto,Keisuke Ishigami,Hisayoshi Igarashi,Reo Maruyama,Kohzoh Imai,Hiroyuki Yamamoto,Yasuhisa Shinomura +13 more
TL;DR: Emerging evidence may provide insights for strategies to target microbiota, immune cells and tumor molecular alterations for colorectal cancer prevention and treatment.
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Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway
Miki Ito,Shinichi Kanno,Katsuhiko Nosho,Yasutaka Sukawa,Kei Mitsuhashi,Hiroyoshi Kurihara,Hisayoshi Igarashi,Taiga Takahashi,Mami Tachibana,Hiroaki Takahashi,Shinji Yoshii,Toshinao Takenouchi,Tadashi Hasegawa,Kenji Okita,Koichi Hirata,Reo Maruyama,Hiromu Suzuki,Kohzoh Imai,Hiroyuki Yamamoto,Yasuhisa Shinomura +19 more
TL;DR: The presence of F. nucleatum was identified in premalignant colorectal lesions regardless of histopathology but was more frequently associated with CIMP‐high lesions, and its positivity increased according to histological grade, suggesting that it may contribute to the progression of coloreCTal neoplasia.
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Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.
Katsuhiko Nosho,Hisayoshi Igarashi,Masanori Nojima,Miki Ito,Reo Maruyama,Shinji Yoshii,Takafumi Naito,Yasutaka Sukawa,Masashi Mikami,Wakana Sumioka,Eiichiro Yamamoto,Sei Kurokawa,Yasushi Adachi,Hiroaki Takahashi,Hiroyuki Okuda,Takaya Kusumi,Masao Hosokawa,Masahiro Fujita,Tadashi Hasegawa,Kenji Okita,Koichi Hirata,Hiromu Suzuki,Hiroyuki Yamamoto,Yasuhisa Shinomura +23 more
TL;DR: In this paper, the authors identify a relationship between specific miRNA molecules and BRAF mutation in colorectal cancers and serrated lesions and demonstrate that miR-31 inhibitor decreased cell invasion and proliferation.
Journal ArticleDOI
Cancer stem cells in human gastrointestinal cancer.
Hiroaki Taniguchi,Chiharu Moriya,Hisayoshi Igarashi,Anri Saitoh,Hiroyuki Yamamoto,Yasushi Adachi,Kohzoh Imai +6 more
TL;DR: This review focuses on the current research on gastrointestinal CSCs and future strategies to abolish the gastrointestinal C SC phenotype, which is very difficult to target.