Holland Kotkiewicz

TL;DR: Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology Laboratory, the Wellcome Trust, and the Howard Hughes Medical Institute.

TL;DR: The data suggest a mechanism where incomplete duplication created a novel gene function-antagonizing parental SRGAP2 function-immediately "at birth" 2-3 mya, which is a time corresponding to the transition from Australopithecus to Homo and the beginning of neocortex expansion.

TL;DR: An empirical reconstruction of human MSY evolution is presented, in which each stratum transitioned from rapid, exponential loss of ancestral genes to strict conservation through purifying selection.

TL;DR: In this article, the authors sequenced the MSY of the rhesus macaque, an Old World monkey, and compared it to the human MSY, finding that during the last 25 million years MSY gene loss in the human lineage was limited to the youngest stratum (stratum 5).