Milinn Kremitzki

TL;DR: It is asserted that the collected updates in GRCh38 make the newer assembly a more robust substrate for comprehensive analyses that will promote the understanding of human biology and advance the efforts to improve health.

TL;DR: High-coverage, ultra-long-read nanopore sequencing is used to create a new human genome assembly that improves on the coverage and accuracy of the current reference (GRCh38) and includes the gap-free, telomere-to-telomere sequence of the X chromosome.

TL;DR: Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology Laboratory, the Wellcome Trust, and the Howard Hughes Medical Institute.

TL;DR: A new version of the chicken genome assembly is presented, built from combined long single molecule sequencing technology, finished BACs, and improved physical maps, and revisited the question of what genes are missing in the avian lineage, and found that a large fraction of the original set of missing genes are still absent in sequenced bird species.

TL;DR: It is asserted that the collected updates in GRCh38 make the newer assembly a more robust substrate for comprehensive analyses that will promote the understanding of human biology and advance the efforts to improve health.