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Lynne V. Nazareth

Researcher at Baylor College of Medicine

Publications -  39
Citations -  28086

Lynne V. Nazareth is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 32, co-authored 38 publications receiving 26237 citations. Previous affiliations of Lynne V. Nazareth include Human Genome Sequencing Center.

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A haplotype map of the human genome

John W. Belmont, +232 more
TL;DR: A public database of common variation in the human genome: more than one million single nucleotide polymorphisms for which accurate and complete genotypes have been obtained in 269 DNA samples from four populations, including ten 500-kilobase regions in which essentially all information about common DNA variation has been extracted.
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A second generation human haplotype map of over 3.1 million SNPs

Kelly A. Frazer, +237 more
- 18 Oct 2007 - 
TL;DR: The Phase II HapMap is described, which characterizes over 3.1 million human single nucleotide polymorphisms genotyped in 270 individuals from four geographically diverse populations and includes 25–35% of common SNP variation in the populations surveyed, and increased differentiation at non-synonymous, compared to synonymous, SNPs is demonstrated.
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Genome-wide detection and characterization of positive selection in human populations

Pardis C. Sabeti, +258 more
- 18 Oct 2007 - 
TL;DR: ‘Long-range haplotype’ methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population are developed.
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Insights into social insects from the genome of the honeybee Apis mellifera

George M. Weinstock, +228 more
- 26 Oct 2006 - 
TL;DR: The genome sequence of the honeybee Apis mellifera is reported, suggesting a novel African origin for the species A. melliferA and insights into whether Africanized bees spread throughout the New World via hybridization or displacement.
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The Drosophila melanogaster Genetic Reference Panel

TL;DR: The Drosophila melanogaster Genetic Reference Panel is described, a community resource for analysis of population genomics and quantitative traits, which reveals reduced polymorphism in centromeric autosomal regions and the X chromosomes, evidence for positive and negative selection, and rapid evolution of the X chromosome.