Hua Yue

TL;DR: Results show that the cellular uptake rate and amount are both positively correlated with the surface charge in all cell line, and subsequent intracellular trafficking indicates that some of positively charged NPs could escape from lysosome after being internalized and exhibit perinuclear localization.

TL;DR: Insight is provided into selective internalization, size-independent uptake, and several other biological behaviors undergone by GO, which might help build necessary knowledge for potential incorporation of the unique two-dimensional nanomaterial as a biomedical tool, and for avoiding potential hazards.

TL;DR: Enzymatic catalysis in living cells enables the in-situ detection of cellular metabolites in single cells, which could contribute to early diagnosis of diseases, and encapsulated enzymes in amorphous MOFs via a one-pot co-precipitation process under ambient conditions led to higher enzymatic activity than in a corresponding crystalline MOF composite.

TL;DR: A novel biomimetic immuno-magnetosome (IMS) is developed by coating a leukocyte membrane (decorated with anti-epithelial cell-adhesion molecule antibody) on a magnetic nanocluster, which exhibits satisfactory binding avidity to circulating tumor cells but stealth property to leukocytes.

TL;DR: Pickering emulsions are developed that retain the force-dependent deformability and lateral mobility of presented antigens while displaying high biosafety and antigen-loading capabilities and may provide a facile, effective, safe and broadly applicable strategy to enhance adaptive immunity against infections and diseases.