Hussain Badani

TL;DR: Risks for mortality, AKI, and myocardial injury were apparent at 85 mmHg, and for mortality and AKI risk progressively worsened at lower thresholds, and Maintaining MAP well above 65 mmHg may be prudent in septic ICU patients.

TL;DR: It is proposed that an approach that focuses on the interfacial hydrophobicity of putative entry inhibitors could lead to the efficient discovery of novel, broad-spectrum viral entry inhibitors.

TL;DR: There is increasing evidence that HSV-1 and VZV latency is epigenetically regulated, and in vitro models that permit pathway analysis and identification of both epigenetic modulations and global transcriptional mechanisms hold much promise for the future understanding in this complex area.

TL;DR: It is shown that subordinate mice experience higher levels of anxiety and display disorganized patterning of their grooming behaviors, which emerges as a behavioral marker of chronic social stress.

TL;DR: It is provided the first demonstration that VZV downregulates PD-L1 expression in infected HBVAFs, HPNCs, and HFLs, which, together with the noted VzV-mediated downregulation of MHC-I, might foster persistent inflammation in vessels, leading to pathological vascular remodeling during VZv vasculopathy and persistence in infected lungs to promote subsequent infection of T cells and hematogenous virus spread.