Hyun-Dong Chang

TL;DR: It is shown here that eosinophils in the vicinity of long‐lived PCs are vigorously proliferating cells and represent a dynamic component of the survival niche, suggesting that memory PC niches may provide attraction for eos inophils to maintain stability with fluctuating yet essential accessory cells.

TL;DR: In this article, the authors show that memory CD8+ T-cells individually colocalize with IL-7+ reticular stromal cells and are maintained as resting cells in the BM in dedicated niches.

TL;DR: The data imply that B‐cell‐derived IL‐10 not only suppresses immune reactions via paracrine mechanisms, but can also contribute to the differentiation ofIL‐10‐secreting B cells into IgM‐ and IgG‐ Secreting plasmablasts through both autocrine and paracine signaling.

TL;DR: The conserved intronic regulatory element links the initial epigenetic modification of the il4 gene to GATA-3 and serves as a genetic control element for memory expression of IL-4.

TL;DR: It is shown that the single deletion of MCs, basophils, or phagocytes (ie, macrophages) prevents the most significant clinical outcome: death, and interventions targeting a single pathway (eg, MC-IgE) might not be sufficient to fully prevent anaphylactic responses.