T
Tai-Chung Huang
Researcher at National Taiwan University
Publications - 36
Citations - 2963
Tai-Chung Huang is an academic researcher from National Taiwan University. The author has contributed to research in topics: Stable isotope labeling by amino acids in cell culture & Proteomics. The author has an hindex of 18, co-authored 33 publications receiving 2582 citations. Previous affiliations of Tai-Chung Huang include Johns Hopkins University School of Medicine & Johns Hopkins University.
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Journal ArticleDOI
A draft map of the human proteome
Min-Sik Kim,Sneha M. Pinto,Derese Getnet,Raja Sekhar Nirujogi,Srikanth S. Manda,Raghothama Chaerkady,Anil K. Madugundu,Dhanashree S. Kelkar,Ruth Isserlin,Shobhit Jain,Joji Kurian Thomas,Babylakshmi Muthusamy,Pamela Leal-Rojas,Pamela Leal-Rojas,Praveen Kumar,Nandini A. Sahasrabuddhe,Lavanya Balakrishnan,Jayshree Advani,Bijesh George,Santosh Renuse,Lakshmi Dhevi N. Selvan,Arun H. Patil,Vishalakshi Nanjappa,Aneesha Radhakrishnan,Samarjeet Prasad,Tejaswini Subbannayya,Rajesh Raju,Manish Kumar,Sreelakshmi K. Sreenivasamurthy,Arivusudar Marimuthu,Gajanan Sathe,Sandip Chavan,Keshava K. Datta,Yashwanth Subbannayya,Apeksha Sahu,Soujanya D. Yelamanchi,Savita Jayaram,Pavithra Rajagopalan,Jyoti Sharma,Krishna R Murthy,Nazia Syed,Renu Goel,Aafaque Ahmad Khan,Sartaj Ahmad,Gourav Dey,Keshav Mudgal,Aditi Chatterjee,Tai-Chung Huang,Jun Zhong,Xinyan Wu,Patrick G. Shaw,Donald Freed,Muhammad Saddiq Zahari,Kanchan K Mukherjee,Subramanian Shankar,Anita Mahadevan,Henry H N Lam,Chris J. Mitchell,Susarla K. Shankar,Parthasarathy Satishchandra,John T. Schroeder,Ravi Sirdeshmukh,Anirban Maitra,Steven D. Leach,Charles G. Drake,Marc K. Halushka,T. S. Keshava Prasad,Ralph H. Hruban,Candace L. Kerr,Candace L. Kerr,Gary D. Bader,Christine A. Iacobuzio-Donahue,Harsha Gowda,Akhilesh Pandey +73 more
TL;DR: A draft map of the human proteome is presented using high-resolution Fourier-transform mass spectrometry to discover a number of novel protein-coding regions, which includes translated pseudogenes, non-c coding RNAs and upstream open reading frames.
Journal ArticleDOI
WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system
Hsin-An Hou,Tai-Chung Huang,Liang-In Lin,Chieh-Yu Liu,Chien-Yuan Chen,Wen-Chien Chou,Jih-Luh Tang,Mei-Hsuan Tseng,Chi-Fei Huang,Ying-Chieh Chiang,Fen-Yu Lee,Ming-Chih Liu,Ming Yao,Shang-Yi Huang,Bor-Sheng Ko,Szu-Chun Hsu,Shang-Ju Wu,Woei Tsay,Yao-Chang Chen,Hwei-Fang Tien +19 more
TL;DR: It is demonstrated that WT1 mutations are correlated with poor prognosis in AML patients and an independent poor prognostic factor for overall survival and relapse-free survival among total patients and the CN-AML group.
Journal ArticleDOI
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.
Yu Yu,Stephanie Gaillard,Jude M. Phillip,Tai-Chung Huang,Sneha M. Pinto,Nayara G. Tessarollo,Nayara G. Tessarollo,Zhen Zhang,Akhilesh Pandey,Denis Wirtz,Ayse Ayhan,Ayse Ayhan,Ben Davidson,Ben Davidson,Tian Li Wang,Ie Ming Shih +15 more
TL;DR: It is reported that recurrent ovarian carcinomas after paclitaxel/carboplatin treatment have higher levels of spleen tyrosine kinase (SYK) and phospho-SYK, and targeting SYK pathway is a promising strategy to enhance pac litaxel response.
Journal ArticleDOI
TSLP signaling pathway map: a platform for analysis of TSLP-mediated signaling.
Jun Zhong,Jyoti Sharma,Rajesh Raju,Shyam Mohan Palapetta,T. S. Keshava Prasad,T. S. Keshava Prasad,Tai-Chung Huang,Akinori Yoda,Jeffrey W. Tyner,Diederik van Bodegom,David M. Weinstock,Steven F. Ziegler,Akhilesh Pandey +12 more
TL;DR: The TSLP signaling pathway map is presented, expecting that it will provide a rich resource to study the biology of this important cytokine as well as to identify novel therapeutic targets for diseases associated with dysregulated T SLP/TSLPR signaling.
Journal ArticleDOI
Identifying targets of miR-143 using a SILAC-based proteomic approach
Yi Yang,Raghothama Chaerkady,Kumaran Kandasamy,Tai-Chung Huang,Lakshmi Dhevi N. Selvan,Sutopa B. Dwivedi,Oliver A. Kent,Joshua T. Mendell,Akhilesh Pandey +8 more
TL;DR: In this paper, a SILAC-based quantitative proteomic strategy was employed to systematically identify potential targets of miR-143, which is a miRNA involved in tumorigenesis in multiple types of cancer, smooth muscle cell fate and adipocyte differentiation.