I
Igor Nazarenko
Researcher at Business International Corporation
Publications - 12
Citations - 2156
Igor Nazarenko is an academic researcher from Business International Corporation. The author has contributed to research in topics: Cancer & Genome. The author has an hindex of 8, co-authored 12 publications receiving 2057 citations.
Papers
More filters
Journal ArticleDOI
Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays
Radoje Drmanac,Andrew B. Sparks,Matthew J. Callow,Aaron L. Halpern,Norman L. Burns,Bahram G. Kermani,Paolo Carnevali,Igor Nazarenko,Geoffrey B. Nilsen,George Yeung,Fredrik A. Dahl,Andres Fernandez,Bryan Staker,Krishna Pant,Jonathan Baccash,Adam P. Borcherding,Anushka Brownley,Ryan J. Cedeno,Linsu Chen,Daniel F. Chernikoff,Alex Cheung,Razvan Chirita,Benjamin Curson,Jessica Ebert,Coleen R. Hacker,Robert Hartlage,Brian Hauser,Steve Huang,Yuan Jiang,Vitali Karpinchyk,Mark Koenig,Calvin Kong,Tom Landers,Catherine Le,Jia Liu,Celeste E. McBride,Matt Morenzoni,Robert E. Morey,Karl Mutch,Helena Perazich,Kimberly Perry,Brock A. Peters,Joe Peterson,Charit L. Pethiyagoda,Kaliprasad Pothuraju,Claudia Richter,Abraham M. Rosenbaum,Shaunak Roy,Jay Shafto,Uladzislau Sharanhovich,Karen W. Shannon,Conrad G. Sheppy,Michel Sun,Joseph V. Thakuria,Anne Tran,Dylan Vu,Alexander Wait Zaranek,Xiaodi Wu,Snezana Drmanac,Arnold R. Oliphant,William C. Banyai,Bruce L. Martin,Dennis G. Ballinger,George M. Church,Clifford Reid +64 more
TL;DR: A genome sequencing platform that achieves efficient imaging and low reagent consumption with combinatorial probe anchor ligation chemistry to independently assay each base from patterned nanoarrays of self-assembling DNA nanoballs is described.
Journal ArticleDOI
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
William Lee,Zhaoshi Jiang,Jinfeng Liu,Peter M. Haverty,Yinghui Guan,Jeremy Stinson,Peng Yue,Yan Zhang,Krishna P. Pant,Deepali Bhatt,Connie Ha,Stephanie Johnson,Michael I. Kennemer,Sankar Mohan,Igor Nazarenko,Colin K. Watanabe,Andrew B. Sparks,David S. Shames,Robert Gentleman,Frederic J. de Sauvage,Howard M. Stern,Ajay Pandita,Dennis G. Ballinger,Radoje Drmanac,Zora Modrusan,Somasekar Seshagiri,Zemin Zhang +26 more
TL;DR: A comprehensive view of somatic alterations in a single lung tumour is presented, and the first evidence, to the authors' knowledge, of distinct selective pressures present within the tumour environment is provided.
Journal ArticleDOI
Computational Techniques for Human Genome Resequencing Using Mated Gapped Reads
Paolo Carnevali,Jonathan M. Baccash,Aaron L. Halpern,Igor Nazarenko,Geoffrey B. Nilsen,Krishna Pant,Jessica Ebert,Anushka Brownley,Matt Morenzoni,Vitali Karpinchyk,Bruce K. Martin,Dennis G. Ballinger,Radoje Drmanac +12 more
TL;DR: Novel computational methods developed for accurate calling of SNPs and short substitutions and indels (<100 bp) are described and the same methods apply to evaluation of hypothesized larger, structural variations.
Patent
Method and system for calling variations in a sample polynucleotide sequence with respect to a reference polynucleotide sequence
Paolo Carnevali,Jonathan M. Baccash,Igor Nazarenko,Aaron L. Halpern,Geoffrey B. Nilsen,Bruce K. Martin,Radoje Drmanac +6 more
TL;DR: In this article, the authors present an approach for calling variations in a sample polynucleotide sequence compared to a reference polynotide sequence. But the approach is limited to the case where a likelihood exists that one or more bases of the sample polyclotide sequence are changed from corresponding bases in the reference polyclonal sequence.
Patent
View selection for a multidimensional database
TL;DR: In this paper, a set of all potential views stored in a structure may be stored in the structure and a path in the path may be traversed in an indicated direction through the structure, the path including two or more potential views and beginning at an indicated view.