I
Ilse Patterson
Researcher at University of Cambridge
Publications - 17
Citations - 416
Ilse Patterson is an academic researcher from University of Cambridge. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 13 publications receiving 269 citations.
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Journal ArticleDOI
Quantifying normal human brain metabolism using hyperpolarized [1-13C]pyruvate and magnetic resonance imaging.
James T. Grist,Mary A. McLean,Frank Riemer,Rolf F. Schulte,Surrin S. Deen,Fulvio Zaccagna,Ramona Woitek,Charlie J. Daniels,Joshua D. Kaggie,Tomasz Matys,Ilse Patterson,Rhys Slough,Andrew B. Gill,Anita Chhabra,Rose Eichenberger,Marie-Christine Laurent,Arnaud Comment,Jonathan H. Gillard,Alasdair Coles,Damian J. Tyler,Ian B. Wilkinson,Bristi Basu,David J. Lomas,Martin J. Graves,Kevin M. Brindle,Ferdia A. Gallagher +25 more
TL;DR: Imaging normal brain metabolism with hyperpolarized [1–13C]pyruvate and subsequent quantification, have important implications for interpreting pathological cerebral metabolism in future studies.
Journal ArticleDOI
Imaging breast cancer using hyperpolarized carbon-13 MRI.
Ferdia A. Gallagher,Ramona Woitek,Ramona Woitek,Mary A. McLean,Andrew B. Gill,Raquel Manzano Garcia,Elena Provenzano,Frank Riemer,Joshua D. Kaggie,Anita Chhabra,Stephan Ursprung,James T. Grist,Charlie J. Daniels,Fulvio Zaccagna,Marie-Christine Laurent,Matthew Locke,Sarah Hilborne,Amy Frary,Turid Torheim,Chris Boursnell,Amy Schiller,Ilse Patterson,Rhys Slough,Bruno Carmo,Justine Kane,Heather Biggs,Emma Harrison,Surrin S. Deen,Andrew J. Patterson,Titus Lanz,Zoya Kingsbury,Mark T. Ross,Bristi Basu,Richard D. Baird,David J. Lomas,Evis Sala,James Wason,James Wason,Oscar M. Rueda,Suet-Feung Chin,Ian B. Wilkinson,Martin J. Graves,Jean Abraham,Fiona J. Gilbert,Carlos Caldas,Kevin M. Brindle +45 more
TL;DR: Imaging of hyperpolarized [1-13C]pyruvate metabolism in breast cancer is feasible and demonstrated significant intertumoral and intratumoral metabolic heterogeneity, where lactate labeling correlated with MCT1 expression and hypoxia.
Journal ArticleDOI
Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population
Tristan Barrett,Mary A. McLean,Andrew N. Priest,Edward M. Lawrence,Edward M. Lawrence,Andrew J. Patterson,Brendan Koo,Ilse Patterson,Anne Y. Warren,Andrew Doble,Vincent Jeyaseelan Gnanapragasam,Christof Kastner,Ferdia A. Gallagher +12 more
TL;DR: Divergent MTR/DKI values in TZ tumours suggests they offer different functional information, and there was no incremental value for DKI/MTI over mono-exponential ADC parameters.
Journal ArticleDOI
Hyperpolarized 13C MRI of Tumor Metabolism Demonstrates Early Metabolic Response to Neoadjuvant Chemotherapy in Breast Cancer
Ramona Woitek,Mary A. McLean,Andrew B. Gill,James T. Grist,Elena Provenzano,Andrew J. Patterson,Stephan Ursprung,Turid Torheim,Fulvio Zaccagna,Matthew Locke,Marie-Christine Laurent,Sarah Hilborne,Amy Frary,Lucian Beer,Leonardo Rundo,Ilse Patterson,Rhys Slough,Justine Kane,Heather Biggs,Emma Harrison,Titus Lanz,Bristi Basu,Richard D. Baird,Evis Sala,Martin J. Graves,Fiona J. Gilbert,Jean Abraham,Carlos Caldas,Kevin M. Brindle,Ferdia A. Gallagher +29 more
TL;DR: Hyperpolarized 13C MRI enabled successful identification of breast cancer response after one cycle of neoadjuvant chemotherapy and may improve response prediction when used in conjunction with multiparametric proton MRI.
Journal ArticleDOI
Quantitative BOLD imaging at 3T: Temporal changes in hepatocellular carcinoma and fibrosis following oxygen challenge.
Andrew J. Patterson,Andrew N. Priest,David J. Bowden,Tess E. Wallace,Ilse Patterson,Martin J. Graves,David J. Lomas +6 more
TL;DR: To evaluate the utility of oxygen challenge and report on temporal changes in blood oxygenation level‐dependent (BOLD) contrast in normal liver, hepatocellular carcinoma (HCC) and background fibrosis, a large number of animals were studied.