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Isamu Hoshino
Researcher at Chiba University
Publications - 121
Citations - 2573
Isamu Hoshino is an academic researcher from Chiba University. The author has contributed to research in topics: Cancer & Esophageal cancer. The author has an hindex of 24, co-authored 110 publications receiving 2182 citations. Previous affiliations of Isamu Hoshino include Michigan State University.
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miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
Masayuki Kano,Naohiko Seki,Naoko Kikkawa,Lisa Fujimura,Isamu Hoshino,Yasunori Akutsu,Takeshi Chiyomaru,Hideki Enokida,Masayuki Nakagawa,Hisahiro Matsubara +9 more
TL;DR: The identification of tumor‐suppressive miRNAs,miR‐145, miR‐133a and miR-133b, directly control oncogenic FSCN1 gene, and could provide new insights into potential mechanisms of ESCC carcinogenesis.
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Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma
Nobuyoshi Takeshita,Isamu Hoshino,Mikito Mori,Yasunori Akutsu,Naoyuki Hanari,Yasuo Yoneyama,Norimasa Ikeda,Yuka Isozaki,Tetsurou Maruyama,Naoki Akanuma,Aki Komatsu,M Jitsukawa,Hiromasa Matsubara +12 more
TL;DR: These data support the contention that serum miR-1246 has strong potential as a novel diagnostic and prognostic biomarker in ESCC, and its releasing mechanism is selective and independent of tissue miRNA abundance.
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The overall prevalence of metastasis in T1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients
Yasunori Akutsu,Masaya Uesato,Kiyohiko Shuto,Tsuguaki Kono,Isamu Hoshino,Daisuke Horibe,Testutaro Sazuka,Nobuyoshi Takeshita,Tetsuro Maruyama,Yuka Isozaki,Naoki Akanuma,Hisahiro Matsubara +11 more
TL;DR: This study provides a precise assessment of the comprehensive risk of metastasis and feasible predictive markers for T1 ESCC.
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Pre-operative dental brushing can reduce the risk of postoperative pneumonia in esophageal cancer patients
Yasunori Akutsu,Hisahiro Matsubara,Kiyohiko Shuto,Toru Shiratori,Masaya Uesato,Yukimasa Miyazawa,Isamu Hoshino,Kentaro Murakami,Akihiro Usui,Masayuki Kano,Hideaki Miyauchi +10 more
TL;DR: Frequent pre-operative dental brushing is performed easily and seems to prevent postoperative pneumonia in esophageal cancer patients.
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MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer
Naoki Akanuma,Isamu Hoshino,Yasunori Akutsu,Kentarou Murakami,Yuka Isozaki,Tetsurou Maruyama,Gulbostan Yusup,Wei Qin,Takeshi Toyozumi,Masahiko Takahashi,Hiroshi Suito,Xin Hu,Nobufumi Sekino,Hiromasa Matsubara +13 more
TL;DR: The combined expression of FSCN1 and MMP14 is associated with a poor prognosis, and miR-133a, which regulates their mRNAs, can serve as a strong tumour suppressor of ESCC.