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Istvan Jona
Researcher at University of Debrecen
Publications - 51
Citations - 2009
Istvan Jona is an academic researcher from University of Debrecen. The author has contributed to research in topics: Ryanodine receptor & Calcium. The author has an hindex of 22, co-authored 51 publications receiving 1934 citations. Previous affiliations of Istvan Jona include State University of New York System & Hungarian Academy of Sciences.
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The effect of dicyclohexycarbodiimide and cyclopiazonic acid on the difference FTIR spectra of sarcoplasmic reticulum induced by photolysis of caged-ATP and caged-Ca2+
TL;DR: It is proposed that both the Ca2- and the ATP-induced difference FTIR spectra of the Ca(2+)-ATPase reflect the occupancy of the high-affinity Ca2+ transport site of the enzyme.
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Skeletal and cardiac ryanodine receptors bind to the Ca2+-sensor region of dihydropyridine receptor α1C subunit
TL;DR: In this paper, surface plasmon resonance spectroscopy was used to demonstrate that both RyR1 and RyR2 can bind to structural elements of the C-terminal cytoplasmic domain of α1C.
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Charged surface area of maurocalcine determines its interaction with the skeletal ryanodine receptor.
Balázs Lukács,Monika Sztretye,János Almássy,Sándor Sárközi,Beatrix Dienes,Kamel Mabrouk,Cecilia Simut,László Zsolt Szabó,Péter Szentesi,Michel De Waard,Michel De Waard,Michel Ronjat,Michel Ronjat,Istvan Jona,László Csernoch +14 more
TL;DR: The observations indicate that the results from bilayer experiments mimic the in situ effects of MCa on RyR1 and suggest that the effect of the peptide is governed by the large charged surface formed by residues Lys(20), Lys(22), Arg(23, Arg(24), and Lys(8).
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Pressure effects on sacroplasmic reticulum: a Fourier transform infrared spectroscpic study
TL;DR: Vanadate (5 mM), and to a lesser extent Ca2+ (2–20 mM), protected the Ca2-ATPase against pressure-induced changes both in the Amide I and Amide II regions of the spectrum, together with the protection of ATPase activity.
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Altered inhibition of the rat skeletal ryanodine receptor/calcium release channel by magnesium in the presence of ATP
TL;DR: Magnesium-induced inhibition of the skeletal ryanodine receptor/calcium-release channel was studied in the presence and absence of ATP under isolated conditions and in situ, by examining the RyR incorporated into a planar lipid bilayer and the calcium release flux in isolated single fibres mounted in the double Vaseline gap system.