J
J.S. Everatt
Publications - 9
Citations - 655
J.S. Everatt is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 3 citations.
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Journal ArticleDOI
Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa
Houriiyah Tegally,Monika Moir,J.S. Everatt,Marta Giovanetti,Cathrine Scheepers,Eduan Wilkinson,Kathleen Subramoney,Zinhle Makatini,Sikhulile Moyo,Daniel G. Amoako,Cheryl Baxter,Christian L. Althaus,Ugochukwu J. Anyaneji,Dikeledi Kekana,Raquel Viana,Jennifer Giandhari,Richard J Lessells,Tongai Maponga,Dorcas Maruapula,Wonderful T. Choga,Mogomotsi Matshaba,M. Mbulawa,Nokukhanya Msomi,Yeshnee Naidoo,Sureshnee Pillay,Tomasz J. Sanko,James Emmanuel San,Lesley Scott,Lavanya Singh,Nonkululeko A Magini,P. Smith-Lawrence,Wendy S. Stevens,Graeme Dor,D. Tshiabuila,Nicole Wolter,Wolfgang Preiser,Florette K. Treurnicht,Marietjie Venter,G.E. Chiloane,Caitlyn McIntyre,Áine O'Toole,Christopher Ruis,Thomas P. Peacock,Cornelius Roemer,Sergei L. Kosakovsky Pond,Carolyn Williamson,Oliver G. Pybus,Jinal N. Bhiman,Allison J. Glass,Darren P. Martin,Ben Jackson,Andrew Rambaut,O. Laguda-Akingba,Simani Gaseitsiwe,Anne von Gottberg,Tulio de Oliveira +55 more
TL;DR: In this article , the authors identified two new lineages, BA.4 and BA.5, responsible for a fifth wave of infections in South Africa, by using a multinomial logistic regression model.
Posted ContentDOI
Continued Emergence and Evolution of Omicron in South Africa: New BA.4 and BA.5 lineages
Houriiyah Tegally,Monika Moir,J.S. Everatt,Marta Giovanetti,Coenraad L. Van W. Scheepers,Eduan Wilkinson,Kathleen Subramoney,Sylvester R. Moyo,Daniel G. Amoako,Christian L. Althaus,Ugochukwu J. Anyaneji,Dineo Kekana,R. Viana,Jennifer Giandhari,Tongai Maponga,Dorcas Maruapula,W. Choga,Simnikiwe H. Mayaphi,Nokuzola Mbhele,Simani Gaseitsiwe,Nokukhanya Msomi,Yeshnee Naidoo,Sureshnee Pillay,Takamasa Sanko,James Emmanuel San,Lesley Scott,Lavanya Singh,Nicolo Magini,P. Smith-Lawrence,W. J. Stevens,Genia Dor,D. Tshiabuila,Nicole Wolter,Wolfgang Preiser,Florette K. Treurnicht,Marietjie Venter,M. Davids,G.E. Chiloane,Adriano Mendes,Chloe McIntyre,Áine O'Toole,Christopher Ruis,Thomas P. Peacock,Cornelius Roemer,Wi +44 more
TL;DR: Two new lineages, BA.4 and BA.5 have rapidly replaced BA.2 in South Africa and are identified by the proxy marker of S-gene target failure with the TaqPath COVID-19 qPCR assay.
Journal ArticleDOI
Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function
Darren P. Martin,Spyros Lytras,Alexander G. Lucaci,Wolf-Martin Maier,Björn Grüning,Stephen D. Shank,Steven Weaver,Oscar A. MacLean,Richard J. Orton,Philippe Lemey,Maciej F. Boni,Houriiyah Tegally,Gordon William Harkins,Cathrine Scheepers,Jinal N. Bhiman,J.S. Everatt,Daniel G. Amoako,James Emmanuel San,Jennifer Giandhari,Alex Sigal,Carolyn Williamson,Nei-yuan Hsiao,Anne von Gottberg,Arne de Klerk,Robert W. Shafer,David Robertson,Robert J. Wilkinson,B.T. Sewell,Richard J Lessells,Anton Nekrutenko,Allison J. Greaney,Tyler N. Starr,Jesse D. Bloom,Ben Murrell,Eduan Wilkinson,Ravindra K. Gupta,Tulio de Oliveira,Sergei L Kosakovsky Pond +37 more
TL;DR: It is proposed that the mutations in each of the three clusters therefore cooperatively interact to both mitigate their individual fitness costs, and, in combination with other mutations, adaptively alter the function of Spike.
Journal ArticleDOI
Clinical severity of SARS-CoV-2 Omicron BA.4 and BA.5 lineages compared to BA.1 and Delta in South Africa
Nicole Wolter,Waasila Jassat,Sibongile Walaza,Richard Welch,Harry Moultrie,Michelle J. Groome,Daniel G. Amoako,J.S. Everatt,Jinal N. Bhiman,Cathrine Scheepers,Naume Tebeila,Nicola Chiwandire,Mignon du Plessis,N. Govender,Arshad Ismail,Allison J. Glass,Koleka Mlisana,W. Stevens,Florette K. Treurnicht,Kathleen Subramoney,Zinhle Makatini,Nei-yuan Hsiao,Raveen Parboosing,Jeannette Wadula,Hannah S Hussey,Mary-Ann Davies,Andrew Boulle,Anne von Gottberg,Cheryl Cohen +28 more
TL;DR: In this article , the presence/absence of the S-gene target was used as a proxy for SARS-CoV-2 variant/lineage for infections diagnosed using the TaqPath PCR assay between 1 October 2021 and 26 April 2022.
Posted ContentDOI
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function
Darren P. Martin,Spyros Lytras,Alexander G. Lucaci,Wolf-Martin Maier,Björn Grüning,Stephen D. Shank,Steven Weaver,Oscar A. MacLean,Richard J. Orton,Philippe Lemey,Maciej F. Boni,Houriiyah Tegally,Gordon William Harkins,Cathrine Scheepers,Jinal N. Bhiman,J.S. Everatt,Daniel G. Amoako,James Emmanuel San,Jennifer Giandhari,Alex Sigal,Carolyn Williamson,Nei-yuan Hsiao,Anne von Gottberg,Arne de Klerk,Robert W. Shafer,David Robertson,Robert J. Wilkinson,B.T. Sewell,Richard J Lessells,Anton Nekrutenko,Allison J. Greaney,Tyler N. Starr,Jesse D. Bloom,Ben Murrell,Eduan Wilkinson,Ravindra K. Gupta,Tulio de Oliveira,Sergei L Kosakovsky Pond +37 more
TL;DR: It is proposed that the mutations in each of the three clusters of the Omicron S-gene cooperatively interact to both mitigate their individual fitness costs, and adaptively alter the function of Spike.