J
Jacob G. Bundy
Researcher at Imperial College London
Publications - 99
Citations - 7743
Jacob G. Bundy is an academic researcher from Imperial College London. The author has contributed to research in topics: Metabolomics & Metabolite. The author has an hindex of 42, co-authored 95 publications receiving 6897 citations. Previous affiliations of Jacob G. Bundy include Macaulay Institute & King's College London.
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Journal ArticleDOI
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts.
Olaf Beckonert,Hector C. Keun,Timothy M. D. Ebbels,Jacob G. Bundy,Elaine Holmes,John C. Lindon,Jeremy K. Nicholson +6 more
TL;DR: The main NMR spectroscopic applications in modern metabolic research are summarized, and detailed protocols for biofluid and tissue sample collection and preparation are provided, including the extraction of polar and lipophilic metabolites from tissues.
Journal ArticleDOI
Environmental metabolomics: a critical review and future perspectives
TL;DR: This review provides a comprehensive and current overview of environmental metabolomics research, and critically evaluates the contribution that metabolomics has made to the environmental sciences, and highlights and discusses recommendations to advance the understanding of the environment, ecology and evolution using a metabolomics approach.
Journal ArticleDOI
Species Interactions Alter Evolutionary Responses to a Novel Environment
Diane Lawrence,Francesca Fiegna,Volker Behrends,Jacob G. Bundy,Albert B. Phillimore,Thomas Bell,Thomas Bell,Timothy G. Barraclough +7 more
TL;DR: Adaptation to a novel environment is altered by the presence of co-occurring species, which altered the functioning of the experimental ecosystems.
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Metabolomic profiling of rapid cold hardening and cold shock in Drosophila melanogaster.
Johannes Overgaard,Anders Malmendal,Jesper Givskov Sørensen,Jacob G. Bundy,Volker Loeschcke,Niels Chr. Nielsen,Martin Holmstrup +6 more
TL;DR: It is observed that the onset and magnitude of the increased sugar levels correlated tightly with the improved chill tolerance following RCH, suggesting a putative role of cryoprotectants during RCH.
Journal ArticleDOI
Metabolomic profiling of heat stress: hardening and recovery of homeostasis in Drosophila.
Anders Malmendal,Johannes Overgaard,Jacob G. Bundy,Jesper Givskov Sørensen,Niels Chr. Nielsen,Volker Loeschcke,Martin Holmstrup +6 more
TL;DR: The data show that heat hardening permits a quicker return to homeostasis, rather than a reduction of the acute metabolic perturbation, and that the reestablishment of homeostatic importance is important for obtaining maximal heat-hardening effect.