J
Jacob Raber
Researcher at Oregon Health & Science University
Publications - 253
Citations - 13602
Jacob Raber is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Apolipoprotein E & Water maze. The author has an hindex of 53, co-authored 230 publications receiving 11862 citations. Previous affiliations of Jacob Raber include Scripps Health & University of California, San Francisco.
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Journal ArticleDOI
Exposure to Low-Dose 56Fe-Ion Radiation Induces Long-Term Epigenetic Alterations in Mouse Bone Marrow Hematopoietic Progenitor and Stem Cells
Isabelle R. Miousse,Lijian Shao,Jianhui Chang,Wei Feng,Yingying Wang,Antiño R. Allen,Antiño R. Allen,Jennifer Turner,Blair Stewart,Jacob Raber,Daohong Zhou,Igor Koturbash +11 more
TL;DR: The findings suggest that epigenetic reprogramming is possibly involved in the development of radiation-induced genomic instability and thus, may have a causative role in theDevelopment of AML.
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Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders
Mikhail Kalinichev,Emmanuel Le Poul,Christelle Bolea,Francoise Girard,Brice Campo,Massimiliano Fonsi,Isabelle Royer-Urios,Susan E. Browne,Jason M. Uslaner,Matthew J. Davis,Jacob Raber,Robert M. Duvoisin,Simon T. Bate,Ian J. Reynolds,Sonia Poli,Sylvain Celanire +15 more
TL;DR: The pharmacological evaluation of ADX88178 shows good specificity as it had no effect on locomotor activity in mice and rats at efficacious doses, and can be a promising new therapeutic approach for treatment of anxiety, OCD, fear-related disorders, and psychosis.
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Evaluation of a Short-Form of the Berg Card Sorting Test
Christopher J. Fox,Shane T. Mueller,Hilary M. Gray,Hilary M. Gray,Jacob Raber,Brian J. Piper,Brian J. Piper +6 more
TL;DR: Strong correlations between the short and long forms support the Berg Card Sorting Test-64 as an abbreviated alternative for the full-length executive function test.
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CD44 transmembrane receptor and hyaluronan regulate adult hippocampal neural stem cell quiescence and differentiation
Weiping Su,Scott Foster,Rubing Xing,Kerstin Feistel,Kerstin Feistel,Reid H.J. Olsen,Summer F. Acevedo,Jacob Raber,Larry S. Sherman +8 more
TL;DR: It is found that HA and CD44 play important roles in regulating adult neurogenesis, and evidence that HA contributes to age-related reductions in neural stem cell (NSC) expansion and differentiation in the hippocampus is provided.
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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.
Gwendolyn J. McGinnis,David Friedman,Kristina H. Young,Eileen Ruth S. Torres,Charles R. Thomas,Michael J. Gough,Jacob Raber +6 more
TL;DR: Although combined treatment with precision RT and checkpoint inhibitor IT achieved tumor growth control, it affected the brain and induced changes in measures of anxiety, cognitive impairments, and neuroinflammation.