Jacob Raber

TL;DR: Findings imply that androgen receptors (ARs) contribute to spatial learning and memory, posing the question as to whether transgenic expression of AR in female mice might modulate hippocampal-dependentLearning and memory under baseline conditions and after local brain irradiation.

TL;DR: It is found that brains of apoE3 mice respond differently to 137Cs irradiation than those of ApoE2 or apo E4 mice, and at 8 h following irradiation, the number of doublecortin-positive cells was higher in apOE3 than apoN2 or APoE4 mice.

TL;DR: A heritable proclivity for elevated MA self-administration may be associated with impairments in hippocampus-dependent memory and reduced sensitivity to effects of MA on lengthening of the circadian period.

TL;DR: Proton irradiation causes long-term changes in the left ventricle and hippocampus in part through methylation-based epigenetic modifications, and this in turn might identify biomarkers of the radiation response, help identify therapeutic targets, and assess the efficacy of mitigators directed at those targets to minimize, or even prevent detrimentalLong-term effects of proton irradiated on the heart and the brain.

TL;DR: In this article, the effects of a high-fat diet on vascular outcomes are investigated in both humans and animal models, and the differences between species provide an opportunity to explore why some species are protected from the detrimental aspects of high fat-diet-induced dysfunction and to translate these findings into benefits for human health.