J
Jacob Raber
Researcher at Oregon Health & Science University
Publications - 253
Citations - 13602
Jacob Raber is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Apolipoprotein E & Water maze. The author has an hindex of 53, co-authored 230 publications receiving 11862 citations. Previous affiliations of Jacob Raber include Scripps Health & University of California, San Francisco.
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Radiation exposure prior to traumatic brain injury induces responses that differ as a function of animal age
Antiño R. Allen,Kirsten Eilertson,Ayanabha Chakraborti,Sourabh Sharma,Jennifer Baure,Julian Habdank-Kolaczkowski,Barrett D. Allen,Susanna Rosi,Susanna Rosi,Jacob Raber,John R. Fike +10 more
TL;DR: It is suggested that irradiation enhanced a young animal's vulnerability to develop cognitive injury following a subsequent traumatic injury.
Brief Communication Novel object recognition in Apoe / mice improved by neonatal implantation of wild-type multipotential stromal cells
Alexandra Peister,Suzanne Zeitouni,Timothy Pfankuch,Roxanne L. Reger,Darwin J. Prockop,Jacob Raber +5 more
TL;DR: In this article, multipotential bone marrow stromal cells (MSCs) from wild-type (Wt) or apolipoprotein E deficient (Apoe(-/-)) mice were implanted into the cerebral ventricles of Apoe(/-) mice and were associated with enhanced object recognition and increased microtubule-associated protein 2 (MAP2) immunoreactivity in the dentate gyrus.
Journal ArticleDOI
Novel object recognition in Apoe(-/-) mice improved by neonatal implantation of wild-type multipotential stromal cells.
Alexandra Peister,Suzanne Zeitouni,Timothy Pfankuch,Roxanne L. Reger,Darwin J. Prockop,Jacob Raber +5 more
TL;DR: It is shown that MSCs can be used to distinguish developmental from post-developmental effects of a gene knockout and support their therapeutic potential for neurodegenerative diseases.
Journal ArticleDOI
Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species.
TL;DR: E4 mice had greater anxiety‐like and conditioned fear behaviors than WT mice, and these genotype differences were associated with greater levels of ROS in E4 thanWT mice, which might contribute to their higher anxiety levels and enhanced fear conditioning.
Journal ArticleDOI
Impairment in extinction of contextual and cued fear following post-training whole-body irradiation.
TL;DR: The effects of radiation on extinction of contextual fear were more profound than those on the extinction of cued fear and whole-body irradiation elevates contextual and cuedFear memory recall.