J
Jacob Raber
Researcher at Oregon Health & Science University
Publications - 253
Citations - 13602
Jacob Raber is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Apolipoprotein E & Water maze. The author has an hindex of 53, co-authored 230 publications receiving 11862 citations. Previous affiliations of Jacob Raber include Scripps Health & University of California, San Francisco.
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Journal ArticleDOI
Combined exposure to protons and (56)Fe leads to overexpression of Il13 and reactivation of repetitive elements in the mouse lung.
Etienne Nzabarushimana,Sara Prior,Isabelle R. Miousse,Rupak Pathak,Antiño R. Allen,John R. Latendresse,Reid H.J. Olsen,Jacob Raber,Martin Hauer-Jensen,Gregory A. Nelson,Igor Koturbash +10 more
TL;DR: A substantial increase in the expression of cytokine Il13, loss of expression of DNA methyltransferase Dnmt1, and reactivation of LINE-1, SINE B1 retrotransposons, and major and minor satellites are observed and combined exposure to protons and (56)Fe resulted in pronounced molecular alterations in comparison with either source of radiation alone.
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The Polyamine Inhibitor Alpha-Difluoromethylornithine Modulates Hippocampus-Dependent Function after Single and Combined Injuries
Susanna Rosi,Ryan A. Ferguson,Kelly Fishman,Antiño R. Allen,Jacob Raber,Jacob Raber,John R. Fike +6 more
TL;DR: It is shown that DFMO effectively reversed cognitive impairments after all injuries, particularly traumatic brain injury, and the mechanisms responsible for the improvement in cognition after DFMO treatment are not yet clear.
Journal ArticleDOI
Novel images and novel locations of familiar images as sensitive translational cognitive tests in humans
TL;DR: The main focus of this review is to illustrate how object recognition can be used to assess cognition in humans under normal physiological and neurological conditions.
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Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice
TL;DR: The results are consistent with the hypothesis that NF1 functions in mice biochemically to inhibit signaling from Alk through Ras, and indicate that inhibition of Alk activity may cognitively benefit patients with Neurofibromatosis 1.
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Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse
Bridgette D. Semple,Bridgette D. Semple,Linda J. Noble-Haeusslein,Major Gooyit,Kayleen G. Tercovich,Zhihong Peng,Trung T. Nguyen,Valerie A. Schroeder,Mark A. Suckow,Mayland Chang,Jacob Raber,Alpa Trivedi +11 more
TL;DR: Acute and short-term post-injury treatment with p-OH SB-3CT did not ameliorate these long-term behavioral, cognitive, or neuropathological deficits as compared to vehicle-treated controls, suggesting that these deficits were independent of M MP-9 and MMP-2 upregulation.