J
Jacob Raber
Researcher at Oregon Health & Science University
Publications - 253
Citations - 13602
Jacob Raber is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Apolipoprotein E & Water maze. The author has an hindex of 53, co-authored 230 publications receiving 11862 citations. Previous affiliations of Jacob Raber include Scripps Health & University of California, San Francisco.
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Journal ArticleDOI
Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8.
Robert M. Duvoisin,Connie Zhang,Timothy Pfankuch,Heather O'Connor,Jacqueline Gayet-Primo,Salma Quraishi,Jacob Raber +6 more
TL;DR: Whether the diverse phenotypic differences observed in mGluR8–/– mice result from the misregulation of a unique neural pathway, possibly in the thalamus or hypothalamus, or whether they are the consequence of multiple developmental and functional alterations in synaptic transmission, remains to be determined.
Journal ArticleDOI
Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis.
TL;DR: Similar to Drosophila, enhanced performance in spatial memory in Alk mutant mice is found and reduced neurogenesis associated with loss of Alk function is observed.
Journal ArticleDOI
Assessment of cognition in early dementia
Nina Silverberg,Laurie M. Ryan,Maria C. Carrillo,Reisa A. Sperling,Reisa A. Sperling,Ronald C. Petersen,Holly Posner,Peter J. Snyder,Robin C. Hilsabeck,Michela Gallagher,Jacob Raber,Albert Rizzo,Katherine L. Possin,Jonathan W. King,Jeffrey Kaye,Brian R. Ott,Marilyn S. Albert,Molly V. Wagster,John A. Schinka,John A. Schinka,C. Munro Cullum,Sarah E Tomaszewski Farias,David A. Balota,Stephen M. Rao,David A. Loewenstein,Andrew E. Budson,Andrew E. Budson,Jason Brandt,Jennifer J. Manly,Lisa L. Barnes,Adriana M. Strutt,Tamar H. Gollan,Mary Ganguli,Debra Babcock,Irene Litvan,Joel H. Kramer,Tanis J. Ferman +36 more
TL;DR: There is a need for assessments that reflect real‐world situations so as to better assess functional disability and it is especially important to develop assessment tools that are useful in ethnically, culturally, and linguistically diverse populations as well as in individuals with neurodegenerative disease other than AD.
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Mouse behavioural analysis in systems biology
Peter Van Meer,Jacob Raber +1 more
TL;DR: Common behavioural tests used to assess brain function are reviewed, and it is illustrated how behavioural tests are used to increase the understanding of the role of histaminergic neurotransmission in brain function.
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Sex-dependent effects of 56Fe irradiation on contextual fear conditioning in C57BL/6J mice.
TL;DR: The effects of 56Fe irradiation on hippocampus‐dependent contextual fear conditioning are critically modulated by sex, and hippocampus‐independent cued fear conditioning was impaired in female mice but improved in male mice following 56 Fe irradiation.