J
Jacob Raber
Researcher at Oregon Health & Science University
Publications - 253
Citations - 13602
Jacob Raber is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Apolipoprotein E & Water maze. The author has an hindex of 53, co-authored 230 publications receiving 11862 citations. Previous affiliations of Jacob Raber include Scripps Health & University of California, San Francisco.
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Enhanced cued fear memory following post-training whole body irradiation of 3-month-old mice.
TL;DR: The data indicate that whole body X ray irradiation of mice at 3 months of age causes persistent alterations in the fear response and activity levels in a novel environment, while the effects on body weight seem more transient.
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Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral Alterations and Cognitive Impairments and Insoluble Cortical Aβ42 Levels
Sarah Holden,Payel Kundu,Eileen Ruth S. Torres,Reetesh Sudhakar,Destine Krenik,Dmytro Grygoryev,Mitchell S. Turker,Jacob Raber +7 more
TL;DR: It is demonstrated that there are apoE isoform-dependent effects on hAPP/Aβ-induced behavioral alterations and cognitive impairments and cortical insoluble Aβ42 levels in mouse models containing only human APP and APoE.
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Behavioral Phenotypes of Foxg1 Heterozygous Mice
Skyler Younger,Sydney Weber Boutros,Francesca Cargnin,Shin Jeon,Jae Woon Lee,Soo-Kyung Lee,Jacob Raber +6 more
TL;DR: The results suggest that Foxg1 HET mice recapitulate at least some symptoms of the human FS individuals, including increased anxiety in the open field as well as impairment in object recognition, motor coordination, and fear learning and contextual and cued fear memory.
Journal Article
Reliability and Validity of the Brief Problem Monitor: An Abbreviated Form of the Child Behavior Checklist (P1.099)
TL;DR: In this paper, an abbreviated version of the CBCL, the Brief Problem Monitor (BPM), was used to evaluate the reliability and validity of the parent version of CBCL.
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ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways
Payel Kundu,Sarah Holden,Ines L. Paraiso,Reetesh Sudhakar,Chloe McQuesten,Jae-Soo Choi,Cristobal L. Miranda,Claudia S. Maier,Gerd Bobe,Jan F. Stevens,Jacob Raber +10 more
TL;DR: The therapeutic potential for XN to ameliorate HFD-induced cognitive impairments is supported and the importance of considering sex and ApoE isoform in determining who might most benefit from this dietary supplement is highlighted.