Jaime Llodra

TL;DR: Analyzing mouse monocyte subsets in apoE-deficient mice and tracing their differentiation and chemokine receptor usage as they accumulated within atherosclerotic plaques suggests antagonizing CX3CR1 may be effective therapeutically in ameliorating CCR2(+) monocyte recruitment to plaques without impairing their C CR2-dependent responses to inflammation overall.

TL;DR: In this article, lipid mediators lysophosphatidic acid and platelet-activating factor, whose signals are implicated in promoting atherosclerosis, blocked conversion of monocytes into migratory cells and favored their retention in the subendothelium.

TL;DR: In this paper, the authors show that Dendritic cell (DC) migration from the periphery to lymph nodes is regulated by the pattern of genes expressed by DCs themselves and by signals within the surrounding peripheral environment.

TL;DR: It is shown that centrally accumulated TCRs are located on the surface of extracellular microvesicles that bud at the immunological synapse centre, which concludes that the immunology synapse orchestrates TCR sorting and release in extrace cellular microvesicle.

TL;DR: Data suggest that Gr-1int monocytes may be most disposed to become a lymphatic-migrating DCs, and the role of CCR8 in emigration from tissues also applied to human monocyte-derived cells in a model of transendothelial trafficking.