James C. Sullivan

TL;DR: The traits that make Nematostella exceptionally attractive as a model organism are explored, recent research demonstrating the utility of Nem atostella in several different contexts are summarized, and a number of developments likely to further increase that utility in the near future are highlighted.

TL;DR: After failure to achieve SVR with TVR-based treatment, resistant variants are observed in most patients, however, presumably due to the lower fitness of those variants, they tend to be replaced with wild-type virus over time.

TL;DR: In general, HCV variants with lower-level resistance to telaprevir were observed as the dominant species in 0 to 3% of patients, depending on the specific variant, whereas higher-level resistant variants (>25-fold-increased IC50) were not observed.

TL;DR: StellaBase, the Nematostella vectensis Genomics Database, is a web-based resource that will facilitate desktop and bench-top studies of the starlet sea anemone and provides a framework for the integration of additional species-specific databases into CnidBase.

TL;DR: An island biogeography model of the microbial communities inhabiting different niches in human airways is proposed for exploring microbial colonization of healthy and diseased lungs, with the potential to inform understanding of microbial community dynamics and the relevance of microbes detected in different sample types.