J
James P. Butler
Researcher at Harvard University
Publications - 324
Citations - 26460
James P. Butler is an academic researcher from Harvard University. The author has contributed to research in topics: Lung volumes & Obstructive sleep apnea. The author has an hindex of 74, co-authored 321 publications receiving 24090 citations. Previous affiliations of James P. Butler include Tohoku University & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Out-of-equilibrium dynamics in the cytoskeleton of the living cell.
TL;DR: Measurements of rheological properties of the human airway smooth muscle cell are reported using forced nanoscale motions of Arg-Gly-Asp RGD-coated microbeads tightly bound to the cytoskeleton, suggesting that trapping, intermittency, and approach to kinetic arrest represent central mesoscale features linking underlying molecular events to integrative cellular functions.
Journal ArticleDOI
Airway epithelial compression promotes airway smooth muscle proliferation and contraction.
Bo Lan,Bo Lan,Jennifer A. Mitchel,Michael O'Sullivan,Chan Young Park,Jae Hun Kim,William C. Cole,James P. Butler,James P. Butler,Jin-Ah Park +9 more
TL;DR: The data demonstrate that mechanical compression of bronchial epithelial cells contributes to proliferation and basal contraction of airway smooth muscle cells and that augmented contraction depends on epithelial cell-derived endothelin-1.
Journal ArticleDOI
Model for a pump that drives circulation of pleural fluid
TL;DR: The thickness of the fluid layer (h), measured by fluorescence videomicroscopy, was larger for larger fluid viscosity (mu), larger sliding velocity (U), and smaller pressure difference (delta P) between the layer and the channel, in good agreement with the observed Thickness of the pleural space.
Journal ArticleDOI
Interpulse interval sequence of LH in normal men essentially constitutes a renewal process.
TL;DR: Autocorrelation analysis of the sequence of interpulse intervals of LH secretion in normal men supports the hypothesis that the underlying mechanism driving LH secretion is a renewal process.
OtherDOI
Gas Exchange in Body Cavities
TL;DR: In this article, the authors discuss the types of gas cavities and the models of gas flow from cavities, as well as their models of Gas Flux from Cavities, Perfusion Versus Diffusion versus Diffusion Limitation.