J
James P. Butler
Researcher at Harvard University
Publications - 324
Citations - 26460
James P. Butler is an academic researcher from Harvard University. The author has contributed to research in topics: Lung volumes & Obstructive sleep apnea. The author has an hindex of 74, co-authored 321 publications receiving 24090 citations. Previous affiliations of James P. Butler include Tohoku University & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Airflow Shape Is Associated With the Pharyngeal Structure Causing OSA
Pedro R. Genta,Pedro R. Genta,Scott A. Sands,Scott A. Sands,James P. Butler,Stephen H. Loring,Eliot S. Katz,B. Gail Demko,Eric J. Kezirian,David P. White,Andrew Wellman +10 more
TL;DR: Inspiratory flow shape is influenced by the pharyngeal structure causing collapse, and flow shape analysis may be used as a noninvasive tool to help determine the phaya structure cause collapse.
Journal ArticleDOI
Shear flow over a self-similar expanding pulmonary alveolus during rhythmical breathing
TL;DR: In this paper, the effect of lung rhythmical expansion on gas mixing and aerosol dispersion and deposition can be studied using a fluid-mechanical model for an alveolated respiratory unit.
Journal ArticleDOI
Cytoskeletal mechanics in confluent epithelial cells probed through integrins and E-cadherins
TL;DR: The degree of confluency may be associated with different mechanics and functions of the CSK network, and observations of a relatively high cell stiffness probed through integrins compared with the small stiffness Probed through E-cadherins suggests that mechanical force transmission might also be important in regulating cell spreading.
Journal ArticleDOI
Kisspeptin administration to women: a window into endogenous kisspeptin secretion and GnRH responsiveness across the menstrual cycle.
TL;DR: Differences in responses to exogenous kisspeptin across the menstrual cycle suggest thatkisspeptin tone is higher in the early follicular phase compared with other cycle phases, and the mechanisms that determine the timing of GnRH pulse generation in men and women appear to be distinct.
Journal ArticleDOI
Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy.
Scott A. Sands,Scott A. Sands,Bradley A. Edwards,Philip I. Terrill,James P. Butler,Robert L. Owens,Robert L. Owens,Luigi Taranto-Montemurro,Ali Azarbarzin,Melania Marques,L Hess,Erik Smales,Camila Maria de Melo,David P. White,Atul Malhotra,Atul Malhotra,Andrew Wellman +16 more
TL;DR: A subgroup of patients with obstructive sleep apnoea who benefit from stabilising ventilatory control with supplemental oxygen therapy can be recognised by estimating pathophysiological mechanisms from a routine diagnostic sleep study.