J
James Sneyd
Researcher at University of Auckland
Publications - 186
Citations - 11960
James Sneyd is an academic researcher from University of Auckland. The author has contributed to research in topics: Inositol trisphosphate receptor & Calcium. The author has an hindex of 46, co-authored 180 publications receiving 11251 citations. Previous affiliations of James Sneyd include University of California, Los Angeles & University of Michigan.
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Journal ArticleDOI
Calcium waves and oscillations driven by an intercellular gradient of inositol (1,4,5)-trisphosphate.
TL;DR: A passive diffusion of IP3, but not Ca2+, through gap junctions remains the preferred hypothesis for the mechanism underlying mechanically-stimulated intercellular calcium waves and Ca2+ oscillations.
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On the propagation of calcium waves in an inhomogeneous medium
James Sneyd,Jonathan A. Sherratt +1 more
TL;DR: This work investigates how the spacing and size of the activation sites affect the existence and speed of propagating calcium waves and derives analytic expressions for the speed of the advancing wave front in the self-oscillatory case and compares them to numerical results.
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On a Model Mechanism for the Spatial Patterning of Teeth Primordia in the Alligator
P. M. Kulesa,G. C. Cruywagen,Sharon R. Lubkin,P.K. Main,James Sneyd,M.W.J. Ferguson,James D. Murray +6 more
TL;DR: Based on biological data, a reaction-diffusion mechanism is developed which can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw of the alligator, Alligator mississippiensis.
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A stochastic model of calcium puffs based on single-channel data.
TL;DR: It is found that, as the number of IP3Rs increases, the average duration of puffs initially increases but then becomes saturated, whereas the average decay time keeps increasing linearly, which gives rise to the observed asymmetric puff shape.
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A kinetic model of the inositol trisphosphate receptor based on single-channel data.
TL;DR: It is shown that the most complex time-dependent model that can be unambiguously determined from steady-state data is one with three closed states and one open state, and how the rate constants depend on calcium is determined.