J
Jamie Near
Researcher at Douglas Mental Health University Institute
Publications - 102
Citations - 3883
Jamie Near is an academic researcher from Douglas Mental Health University Institute. The author has contributed to research in topics: Medicine & Glutamate receptor. The author has an hindex of 28, co-authored 86 publications receiving 2823 citations. Previous affiliations of Jamie Near include University of Oxford & McGill University.
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Linking GABA and glutamate levels to cognitive skill acquisition during development
TL;DR: It is found that glutamate/GABA levels and gray matter volume are dissociated at the different maturational stages, suggesting that increased excitation during development is linked to neuroplasticity and the acquisition of new cognitive skills.
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Spectroscopy markers of suicidal risk and mental pain in depressed patients.
TL;DR: It is suggested that markers of impaired neuronal and glial functioning in right dorsal prefrontal cortex underlie cardinal symptoms of the suicidal crisis and targeting this region may be relevant for the short‐term suicidal prevention.
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Validation of in vivo MRS measures of metabolite concentrations in the human brain.
Elvisha Dhamala,Ines Abdelkefi,Mavesa Nguyen,Mavesa Nguyen,T. Jay Hennessy,T. Jay Hennessy,Hélène Nadeau,Jamie Near,Jamie Near +8 more
TL;DR: Assessment of the validity of MRS measures of human brain metabolite concentrations by comparing multiple M RS measures acquired using different MRS acquisition sequences.
Pathological glutamatergic neurotransmission in Gilles de la Tourette Syndrome
Ahmad S. Kanaan,Ahmad S. Kanaan,Sarah Gerasch,Isabel García-García,Leonie Lampe,André Pampel,Alfred Anwander,Jamie Near,Kirsten R. Müller-Vahl,Harald E. Möller +9 more
TL;DR: The results indicate that patients with Gilles de la Tourette syndrome exhibit an abnormality in the flux of metabolites in the GABA-Glu-Gln cycle, thus implying perturbations in astrocytic-neuronal coupling systems that maintain the subtle balance between excitatory and inhibitory neurotransmission within subcortical nuclei.
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Multi-vendor standardized sequence for edited magnetic resonance spectroscopy.
Muhammad G. Saleh,Muhammad G. Saleh,Daniel L. Rimbault,Mark Mikkelsen,Georg Oeltzschner,AM Wang,Dengrong Jiang,Ali Alhamud,Jamie Near,Michael Schär,Ralph Noeske,James B. Murdoch,Lars Ersland,Alexander R. Craven,Gerard Eric Dwyer,Eli Renate Grüner,Li Pan,Sinyeob Ahn,Richard A.E. Edden +18 more
TL;DR: An effort to develop a new universal MEGA‐PRESS sequence with HERMES functionality for the major MR vendor platforms with standardized RF pulse shapes, durations, amplitudes and timings is described.