J
Jamma Trinath
Researcher at Birla Institute of Technology and Science
Publications - 20
Citations - 1078
Jamma Trinath is an academic researcher from Birla Institute of Technology and Science. The author has contributed to research in topics: FOXP3 & Antibody. The author has an hindex of 10, co-authored 19 publications receiving 667 citations. Previous affiliations of Jamma Trinath include Indian Institute of Science & French Institute of Health and Medical Research.
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Journal ArticleDOI
Bile acid metabolites control TH17 and Treg cell differentiation
Saiyu Hang,Donggi Paik,Lina Yao,Eunha Kim,Jamma Trinath,Jingping Lu,Soyoung Ha,Brandon N. Nelson,Samantha P. Kelly,Lin Wu,Ye Zheng,Randy S. Longman,Fraydoon Rastinejad,A. Sloan Devlin,Michael R. Krout,Michael A. Fischbach,Dan R. Littman,Dan R. Littman,Jun R. Huh,Jun R. Huh +19 more
TL;DR: Two derivatives of lithocholic acid are revealed that act as regulators of T helper cells that express IL-17a and regulatory T cells, thus influencing host immune responses.
Journal ArticleDOI
Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells
Jamma Trinath,Jamma Trinath,Pushpa Hegde,Pushpa Hegde,Meenu Sharma,Meenu Sharma,Mohan S. Maddur,Mohan S. Maddur,Mohan S. Maddur,Magalie Rabin,Magalie Rabin,Jean Michel Vallat,Laurent Magy,Kithiganahalli Narayanaswamy Balaji,Srini V. Kaveri,Jagadeesh Bayry +15 more
TL;DR: It is demonstrated that IVIg expands Tregs via induction of cyclooxygenase (COX)-2-dependent prostaglandin E2 (PGE2) in human DCs, and that costimulatory molecules of DCs such as programmed death ligands, OX40 ligand, and inducible T-cell costimulator ligands were not implicated.
Journal ArticleDOI
Extracellular small heat shock proteins: exosomal biogenesis and function.
TL;DR: A review aimed at highlighting the current understanding of sHsps (Hsp27, αB-crystallin, and Hsp20) in the extracellular medium and exosomes packaged with sHSps have beneficial effects in in vivo disease models.
Journal ArticleDOI
Mycobacterium tuberculosis Promotes Regulatory T-Cell Expansion via Induction of Programmed Death-1 Ligand 1 (PD-L1, CD274) on Dendritic Cells
Jamma Trinath,Jamma Trinath,Mohan S. Maddur,Mohan S. Maddur,Mohan S. Maddur,Srini V. Kaveri,Kithiganahalli Narayanaswamy Balaji,Jagadeesh Bayry +7 more
TL;DR: The results suggest that the Treg expansion observed by Periasamy et al [5] was indeed attributable to modulation of DC (or innate immune cells in general) functions by M. tuberculosis.
Journal ArticleDOI
Pathogen-specific TLR2 Protein Activation Programs Macrophages to Induce Wnt-β-Catenin Signaling
Kushagra Bansal,Jamma Trinath,Dipshikha Chakravortty,Shripad A. Patil,Kithiganahalli Narayanaswamy Balaji +4 more
TL;DR: A role for differential stimulation of TLR2 is revealed in deciding the strength of Wnt-β-catenin signaling, which together with signals from Notch1 contributes toward the modulation of a defined set of effector functions in macrophages and thus establishes a conceptual framework for the development of novel therapeutics.